4 Pharmacokinetics and Pharmacodynamics William Banner, Jr. Be sure to check out the supplementary content available at http://evolve.elsevier.com/Hazinski. Pearls • Pharmacokinetics describes how the body alters drug concentration, including how…
17 Overview of Solid Organ Transplantation John B. Pietsch Be sure to check out the supplementary content available at http://evolve.elsevier.com/Hazinski. History History of Solid Organ Transplantation Early attempts at solid…
3 Care of the Child with Life-Limiting Conditions and the Child’s Family in the Pediatric Critical Care Unit Mary Jo Gilmer To cure sometimes To relieve often To comfort always…
2 Psychosocial Aspects of Pediatric Critical Care Margaret C. Slota Pearls • The environment and dynamics of a pediatric critical care unit (PCCU) create many challenges for the child, family,…
During the pseudoglandular period, there is a differentiation of the primitive airway epithelium (Post & Copland, 2002). At the time of branching, the bronchi are enveloped in the mesenchyme that…
The pediatric airway has many unique features that differ depending on the age of the child (Table 6.1). The larynx is significantly higher in infants and in children. The inferior…
leukotriene C4 > leukotriene E4. Cys-leukotriene 1 receptors are expressed in airway smooth muscle, tissue macrophages, monocytes, and eosinophils, and cys-leukotriene 2 receptors are found in airway macrophages and smooth…
When the level of airway obstruction is at the lower airway, chest X-ray findings may include hyperinflation, atelectasis, pneumonia, and mediastinal shift. Hyperinflation occurs when there is a “ball-valve” mechanism…
Inspection During the inspection component of the examination, the child should be sitting, if possible. Keep in mind that a younger child may be more comfortable sitting on the parent’s…
Although there are many PCD phenotypes (Bush et al., 2007), only a few are commonly observed. They include the lack of outer dynein arms, a combination of missing inner and…
