Inflammation and Wound Healing

Chapter 12


Inflammation and Wound Healing


Sharon L. Lewis





Reviewed by Trevah A. Panek, RN, MSN, CCRN, Assistant Professor of Nursing, Saint Francis University, Loretto, Pennsylvania; and Clemma K. Snider, RN, MSN, Assistant Professor, Associate Degree Nursing, Eastern Kentucky University, Richmond, Kentucky.


This chapter focuses on inflammation and wound healing. Pressure ulcer prevention and treatment are also described.



Inflammatory Response


The inflammatory response is a sequential reaction to cell injury. It neutralizes and dilutes the inflammatory agent, removes necrotic materials, and establishes an environment suitable for healing and repair. The term inflammation is often but incorrectly used as a synonym for the term infection. Inflammation is always present with infection, but infection is not always present with inflammation. However, a person who is neutropenic may not be able to mount an inflammatory response. An infection involves invasion of tissues or cells by microorganisms such as bacteria, fungi, and viruses. In contrast, inflammation can also be caused by heat, radiation, trauma, chemicals, allergens, and an autoimmune reaction.


The mechanism of inflammation is basically the same regardless of the injuring agent. The intensity of the response depends on the extent and severity of injury and on the injured person’s reactive capacity. The inflammatory response can be divided into a vascular response, a cellular response, formation of exudate, and healing. Fig. 12-1 illustrates the vascular and cellular response to injury.





image eNursing Care Plan 12-1   Patient With a Fever




Patient Goal


Maintains body temperature within normal range





Patient Goal


Maintains adequate fluid volume in the presence of fever




*Nursing diagnoses listed in order of priority



image eNursing Care Plan 12-2   Patient With a Pressure Ulcer




Patient Goals

















Outcomes (NOC) Interventions (NIC) and Rationales
Tissue Integrity: Skin and Mucous Membranes Pressure Ulcer Prevention








• Use an established risk assessment tool to monitor individual’s risk factors (e.g., Braden scale [eTable 12-4]) to reduce or eliminate factors that contribute to development or progression of the pressure ulcer.


• Document any previous incidences of pressure ulcer formation to identify specific risks to patient.


• Remove excessive moisture on the skin resulting from perspiration, wound drainage, and fecal or urinary incontinence to prevent maceration.


• Avoid massaging over bony prominences to prevent further tissue damage.


• Turn every 1 to 2 hours to avoid prolonged pressure in one area.


• Turn with care (e.g., avoid shearing) to prevent injury to fragile skin.


• Position with pillows to elevate pressure points off the bed.


• Use specialty beds and mattresses as needed to provide pressure relief and increase circulation to the site.


• Use devices on the bed (e.g., sheepskin) that protect the individual from pressure.


• Apply elbow and heel protectors as appropriate to avoid pressure.


• Assist individual in maintaining a healthy weight as the risk for pressure ulcers is increased in people who are obese or very thin.



Pressure Ulcer Care


• Describe characteristics of the ulcer at regular intervals, including size (length × width × depth), stage (I to IV), location, exudate, granulation or necrotic tissue, and epithelialization to provide baseline and ongoing data for monitoring pressure ulcer.


• Keep the ulcer moist to aid in healing.


• Cleanse the ulcer with the appropriate nontoxic solution, working in a circular motion from the center to increase circulation to the site.


• Debride ulcer, as needed, to promote new tissue growth.


• Apply a permeable adhesive membrane, saline soaks, ointments, and/or dressings, as appropriate, to promote healing.


• Verify adequate caloric and high-quality protein intake to provide nutrients necessary for tissue repair.


• Teach individual or family member(s) wound care procedures to enhance self-care.


• Instruct family member/caregiver about signs of skin breakdown to prevent recurrence.


• Initiate consultation services of the enterostomal therapy nurse, as needed, for specialized direction of ulcer care.



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eTABLE 12-1


WOUND CLASSIFICATION BY ETIOLOGY































The following classification system is based on the etiology of the wound.
Wound Type Clinical Presentation
Diabetic Ulcers
Ischemic ulcers
Neuropathic ulcers
Vascular Ulcers
Arterial ulcers
Venous ulcers
Pressure ulcers
Atypical wounds


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eTABLE 12-2


WOUND CLASSIFICATION SYSTEMS

































Classification System Description Clinical Use
Surgical Wounds are approximated and heal by primary intention if there are no complications. All surgical incisions
Depth of Skin Destruction (superficial, partial, and full thickness) Superficial has intact and inflamed tissue, partial thickness involves only dermis and epidermis, and full thickness extends through the dermis. Abrasions, burns, skin grafts including donor sites
NPUAP Staging See Table 12-13 in text Pressure ulcers only
Payne-Martin
Skin tears
Meggit-Wagner
Originally developed to classify diabetic foot ulcers. This system has been modified and used with other ulcers and wounds because of descriptors of tissue depth, infection, and necrosis.
University of Texas Grading

Stages


Originally developed for diabetic foot wounds. Has been validated in other locations. This system uses two tiers; grades a wound 0-3 and uses stage descriptors A-D to more specifically describe the wound.


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eTABLE 12-3


BRADEN SCALE FOR PREDICTING PRESSURE SORE RISK












































































































Patient Name ____________________________________ Evaluator’s Name _______________________________
Point Value Date of Assessment and Score
1 2 3 4        
Sensory Perception: Ability to Respond Meaningfully to Pressure-Related Discomfort      
Completely limited: unresponsive (does not moan, flinch, or grasp) to painful stimuli, because of diminished level of consciousness or sedation
OR
limited ability to feel pain over most of body
Very limited: responds only to painful stimuli; cannot communicate discomfort except by moaning or restlessness
OR
has a sensory impairment that limits the ability to feel pain or discomfort over half of body
Slightly limited: responds to verbal commands, but cannot always communicate discomfort or the need to be turned
OR
has some sensory impairment that limits ability to feel pain or discomfort in one or two extremities
No impairment: responds to verbal commands; has no sensory deficit that would limit ability to feel or to voice pain or discomfort        
Moisture: Degree to Which Skin Is Exposed to Moisture      
Constantly moist: skin is kept moist almost constantly by perspiration, urine, etc.; dampness is detected every time patient is moved or turned Very moist: skin is often, but not always, moist; linen must be changed at least once per shift Occasionally moist: skin is occasionally moist, requiring an extra linen change approximately once per day Rarely moist: skin is usually dry; linen only requires changing at routine intervals        
Activity: Degree of Physical Activity      
Bedfast: confined to bed Chairfast: ability to walk severely limited or nonexistent; cannot bear own weight and/or must be assisted into chair or wheelchair Walks occasionally: walks occasionally during day, but for very short distances, with or without assistance; spends most of each shift in bed or chair Walks frequently: walks outside room at least twice per day and inside room at least once every 2 hours during waking hours        
Mobility: Ability to Change and Control Body Position      
Completely immobile: does not make even slight changes in body or extremity position without assistance Very limited: makes occasional slight changes in body or extremity position but unable to make frequent or significant changes independently Slightly limited: makes frequent although slight changes in body or extremity position independently No limitation: makes major and frequent changes in position without assistance        
Nutrition: Usual Food Intake Pattern      
Very poor: never eats a complete meal; rarely eats more than half of any food offered; eats two servings or less of protein (meat or dairy products) per day; takes fluids poorly; does not take a liquid dietary supplement or is NPO and/or maintained on clear liquids or IVs for more than 5 days Probably inadequate: rarely eats a complete meal and generally eats only about half of any food offered; protein intake includes only three servings of meat or dairy products per day; occasionally will take a dietary supplement or receives less than optimum amount of liquid diet or tube feeding Adequate: eats over half of most meals; eats four servings of protein (meat or dairy products) per day; occasionally will refuse a meal, but will usually take a supplement when offered or is on a tube feeding or parenteral nutrition regimen that probably meets most nutritional needs Excellent: eats most of every meal; never refuses a meal; eats four or more servings of protein (meat or dairy products); occasionally eats between meals; does not require supplementation        
Friction and Shear      
Problem: requires moderate to maximum assistance in moving; complete lifting without sliding against sheets is impossible; frequently slides down in bed or chair, requiring frequent repositioning with maximum assistance; spasticity, contractures, or agitation lead to almost constant friction Potential problem: moves feebly or requires minimum assistance; during a move, skin probably slides to some extent against sheets, chair, restraints, or other devices; maintains relatively good position in chair or bed most of the time but occasionally slides down No apparent problem: moves in bed and in chair independently and has sufficient muscle strength to lift up completely during move; maintains good position in bed or chair          
Scoring: To obtain a patient’s pressure ulcer risk assessment score, add the numeric scores for the factors in each of the six subscales (sensory perception, moisture, activity, mobility, nutrition, and friction and shear) to obtain the total score. Scores can range from 6 to 23. The lower the numeric score, the higher the patient’s predicted risk of developing a pressure ulcer. Incremental changes in the score indicate the level of risk: no risk (19 to 23), at risk (15 to 18), moderate risk (13 to 14), high risk (10 to 12), and very high risk (9 or below).      


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Copyright © Barbara Braden and Nancy Bergstrom. All rights reserved. Available at www.bradenscale.com.


From Braden B, Bergstrom N: Predictive validity of the Braden scale for pressure sore risk in a nursing home population, Res Nurs Health 17:459, 1994.



eTABLE 12-4


PRESSURE ULCER SCALE FOR HEALING (PUSH)
PUSH Tool 3.0










Patient Name ___________________________________ Patient ID# __________________
Ulcer Location ___________________________________ Date _______________________



































































Directions
Observe and measure the pressure ulcer. Categorize the ulcer with respect to surface area, exudate, and type of wound tissue. Record a sub-score for each of these ulcer characteristics. Add the sub-scores to obtain the total score. A comparison of total scores measured over time provides an indication of the improvement or deterioration in pressure ulcer healing.
LENGTH × WIDTH (in cm2) 0
0
1
<0.3
2
0.3-0.6
3
0.7-1.0
4
1.1-2.0
5
2.1-3.0
Sub-score
    6
3.1-4.0
7
4.1-8.0
8
8.1-12.0
9
12.1-24.0
10
>24.0
 
EXUDATE AMOUNT 0
None
1
Light
2
Moderate
3
Heavy
    Sub-score
TISSUE TYPE 0
Closed
1
Epithelial Tissue
2
Granulation Tissue
3
Slough
4
Necrotic Tissue
  Sub-score
  TOTAL SCORE
Length × Width
Measure the greatest length (head to toe) and the greatest width (side to side) using a centimeter ruler. Multiply these two measurements (length × width) to obtain an estimate of surface area in square centimeters (cm2). caveat: Do not guess! Always use a centimeter ruler and always use the same method each time the ulcer is measured.
Exudate Amount
Estimate the amount of exudate (drainage) present after removal of the dressing and before applying any topical agent to the ulcer. Estimate the exudate (drainage) as none, light, moderate, or heavy.
Tissue Type
This refers to the types of tissue that are present in the wound (ulcer) bed. Score as a “4” if there is any necrotic tissue present. Score as a “3” if there is any amount of slough present and necrotic tissue is absent. Score as a “2” if the wound is clean and contains granulation tissue. A superficial wound that is reepithelializing is scored as a “1.” When the wound is closed, score as a “0.”

www.npuap.org PUSH Tool Version 3.0: 9/15/98.
11F ©National Pressure Ulcer Advisory Panel.
Pressure Ulcer Healing Chart
To monitor trends in PUSH Scores over time














Patient Name ___________________________________ Patient ID# ________________
Ulcer Location ___________________________________ Date _____________________
Directions
Observe and measure pressure ulcers at regular intervals using the PUSH Tool.
Date and record PUSH Sub-scores and Total Scores on the Pressure Ulcer Healing Record below.









































































































































































































































































































































































































Pressure Ulcer Healing Record
Date                            
Length × width                            
Exudate amount                            
Tissue type                            
PUSH Total Score                            
Graph the PUSH Total Scores on the Pressure Ulcer Healing Graph below.
PUSH Total Score Pressure Ulcer Healing Graph
17                            
16                            
15                            
14                            
13                            
12                            
11                            
10                            
9                            
8                            
7                            
6                            
5                            
4                            
3                            
2                            
1                            
Healed = 0                            
Date                            


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Nov 17, 2016 | Posted by in NURSING | Comments Off on Inflammation and Wound Healing

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