Syphilis Natural history of untreated syphilis Syphilis is caused by the spirochete bacterium, Treponema pallidum, which enters the body through miniscule breaks in the skin of the external genitalia that…
Testicular cancer is the most common malignancy in men in the 20–40-year age group. The germ-cell tumors (GCTs) are the most prevalent type of testicular cancer. Their incidence has risen…
Gonorrhea Gonorrhea is the most frequently reported communicable disease in many of the more developed countries. Rates are 5–50 times higher than in the less developed world. The Gram-negative coccus…
Invasive squamous cell carcinoma accounts for 80% of cervical malignancies. Unlike the remainder of the reproductive tract cancers, which are more prevalent in industrialized countries, cervical cancer ranks second in…
Imprinting Imprinting is the differential expression of a gene or set of genes that is determined by whether that genetic material was inherited from the mother or from the father….
Clinical spectrum of pre-eclampsia Pre-eclampsia is a unique disorder found only in human pregnancies. Historically, pre-eclampsia has been defined as the triad of hypertension, proteinuria and edema in a pregnant…
Twins may arise from one of two mechanisms: division of a single fertilized ovum into two embryos (“identical” or monozygotic twins) or fertilization of two separate ova (“fraternal” or dizygotic…
The etiologies of primary and secondary amenorrhea often overlap. Those more commonly associated with primary amenorrhea are discussed in Chapter 30. Most secondary amenorrhea results from anovulation. The most common…
Structural anomalies Structural anomalies of the uterus, cervix and vagina are the most common abnormalities of sexual differentiation seen in women. They arise from embryologic abnormalities of Müllerian system development…
Hyperprolactinemia is a common clinical problem. Cases resulting from inappropriate prolactin secretion by the pituitary gland are the third most frequently diagnosed cause of chronic anovulation and secondary amenorrhea. There…
