CHAPTER 71 Cyclooxygenase inhibitors: Nonsteroidal anti-inflammatory drugs and acetaminophen Mechanism of Action Classification of Cyclooxygenase Inhibitors First-Generation NSAIDs Aspirin Nonaspirin First-Generation NSAIDs Second-Generation NSAIDs (COX-2 Inhibitors, Coxibs) Celecoxib Rofecoxib and…
CHAPTER 76 Drugs for asthma BASIC CONSIDERATIONS Pathophysiology of Asthma Overview of Drugs for Asthma Administering Drugs by Inhalation ANTI-INFLAMMATORY DRUGS Glucocorticoids Leukotriene Modifiers Zileuton Zafirlukast Montelukast Cromolyn Omalizumab BRONCHODILATORS…
CHAPTER 32 Antidepressants MAJOR DEPRESSION: CLINICAL FEATURES, PATHOGENESIS, AND TREATMENT OVERVIEW DRUGS USED FOR DEPRESSION Basic Considerations Selective Serotonin Reuptake Inhibitors (SSRIs) Fluoxetine Other SSRIs Serotonin/Norepinephrine Reuptake Inhibitors (SNRIs) Venlafaxine…
CHAPTER 102 Anticancer drugs I: cytotoxic agents Introduction to the Cytotoxic Anticancer Drugs Mechanisms of Cytotoxic Action Cell-Cycle Phase Specificity Toxicity Dosage, Handling, and Administration Alkylating Agents Shared Properties Properties…
CHAPTER 51 Drugs for angina pectoris Determinants of Cardiac Oxygen Demand and Oxygen Supply Angina Pectoris: Pathophysiology and Treatment Strategy Chronic Stable Angina (Exertional Angina) Variant Angina (Prinzmetal’s Angina, Vasospastic…
CHAPTER 67 Review of the immune system Introduction to the Immune System Natural Immunity Versus Specific Acquired Immunity Cell-Mediated Immunity Versus Antibody-Mediated (Humoral) Immunity Introduction to Cells of the Immune…
CHAPTER 5 Pharmacodynamics Dose-Response Relationships Basic Features of the Dose-Response Relationship Maximal Efficacy and Relative Potency Drug-Receptor Interactions Introduction to Drug Receptors The Four Primary Receptor Families Receptors and Selectivity…
CHAPTER 24 Drugs for epilepsy Seizure Generation Types of Seizures Partial Seizures Generalized Seizures Mixed Seizures: Lennox-Gastaut Syndrome How Antiepileptic Drugs Work Basic Therapeutic Considerations Therapeutic Goal and Treatment Options…
CHAPTER 104 Drugs for the eye Drugs for Glaucoma Pathophysiology and Treatment Overview Drugs Used to Treat Glaucoma Cycloplegics and Mydriatics Anticholinergic Agents Phenylephrine (an Adrenergic Agonist) Drugs for Allergic…
CHAPTER 68 Childhood immunization General Considerations Definitions Public Health Impact of Immunization Reporting Vaccine-Preventable Diseases Immunization Records Adverse Effects of Immunization Vaccine Information Statements Childhood Immunization Schedule Target Diseases Measles,…
