I ibandronate eye-ban-droe-nate (Boniva) classification PHARMACOTHERAPEUTIC: Bisphosphonate. CLINICAL: Calcium regulator (see p. 142C). Action Binds to bone hydroxyapatite (part of mineral matrix of bone), inhibits osteoclast activity. Therapeutic Effect: Reduces…
L labetalol la-bay-ta-lol (Apo-Labetalol , Normodyne , Trandate) Do not confuse labetalol with betaxolol, metoprolol or propranolol, or Trandate with tramadol or Trental. Fixed-combination(s) Normozide: labetalol/hydrochlorothiazide (a diuretic): 100 mg/25…
E ecallantide e-kal-an-tide (Kalbitor) BLACK BOX ALERT Risk of anaphylactic reaction. Must be administered by health care personnel with appropriate support to manage anaphylaxis, hereditary angioedema and an understanding of…
H haloperidol hal-o-per-i-dol (Apo-Haloperidol , Haldol, Haldol Decanoate, Novo-Peridol ) BLACK BOX ALERT Increased risk of mortality in elderly pts with dementia-related psychosis with use of injections. Do not confuse…
S salmeterol sal-met-er-all (Serevent Diskhaler , Serevent Diskus) BLACK BOX ALERT Long-acting beta2-adrenergic agonists may increase risk of asthma-related deaths and asthma-related hospitalizations in pediatric and adolescents. Use only as…
B baclofen bak-loe-fen (Apo-Baclofen , Lioresal, Novo-Baclofen , Nu-Baclo ) BLACK BOX ALERT Abrupt withdrawal of intrathecal form has resulted in severe hyperpyrexia, obtundation, rebound or exaggerated spasticity, muscle rigidity,…
R rabeprazole rah-bep-rah-zole (Aciphex, Apo-Rabeprazole) Do not confuse Aciphex with Accupril or Aricept, or rabeprazole with aripiprazole, lansoprazole, omeprazole, or raloxifene. classification PHARMACOTHERAPEUTIC: Proton pump inhibitor. CLINICAL: Gastric acid inhibitor…
P paclitaxel pak-li-tak-sel (Abraxane, Apo-Paclitaxel ) BLACK BOX ALERT Myelosuppression is major dose-limiting toxicity. Must be administered by certified chemotherapy personnel. Severe hypersensitivity reactions reported. Do not confuse paclitaxel with…
A abacavir a-bak-a-veer (Ziagen) BLACK BOX ALERT Serious, sometimes fatal hypersensitivity reactions, lactic acidosis, severe hepatomegaly with steatosis (fatty liver) have occurred. Fixed-combination(s) Epzicom: abacavir/lamivudine (antiretroviral): 600 mg/300 mg. Trizivir:…
Z zafirlukast za-fir-loo-kast (Accolate) Do not confuse Accolate with Accupril, Accutane, or Aclovate. classification PHARMACOTHERAPEUTIC: Leukotriene receptor antagonist. CLINICAL: Antiasthma (see p. 78C). Action Binds to leukotriene receptors, inhibiting bronchoconstriction…