M macitentan ma-si-ten-tan (Opsumit) BLACK BOX ALERT Do not administer during pregnancy. May cause fetal harm. Exclude pregnancy before, during, and at least 1 mo after treatment. Treatment of female…

N nabumetone na-bue-me-tone (Apo-Nabumetone , Novo-Nabumetone , Relafen ) BLACK BOX ALERT Increased risk of serious cardiovascular thrombotic events, including myocardial infarction, CVA. Increased risk of severe GI reactions, including…

D dabigatran dab-ih-gah-tran (Pradaxa, Pradax ) classification PHARMACOTHERAPEUTIC: Thrombin inhibitor. CLINICAL: Anticoagulant (see p. 32C). Action Direct thrombin inhibitor, preventing the conversion of fibrinogen into fibrin during coagulation cascade. Therapeutic…

V valacyclovir val-a-sye-kloe-veer (Apo-Valacyclovir , Valtrex) Do not confuse valacyclovir with acyclovir or valganciclovir, or Valtrex with Valcyte. classification PHARMACOTHERAPEUTIC: Antiviral. CLINICAL: Antiherpetic agent (see p. 71C). Action Converted to…

C cabazitaxel ka-baz-i-tax-el (Jevtana) BLACK BOX ALERT All pts should be premedicated with a corticosteroid, an antihistamine, and an H2 antagonist prior to infusion. Severe hypersensitivity reaction has occurred. Immediately…

T tacrolimus tak-roe-li-mus (Advagraf , Prograf, Protopic) BLACK BOX ALERT Increased susceptibility to infection and potential for development of lymphoma. Topical form associated with rare cases of malignancy. Topical form…

O obinutuzumab oh-bi-nue-tooz-ue-mab (Gazyva) BLACK BOX ALERT Hepatitis B reactivation resulting in hepatic failure, fulminant hepatitis, and death have occurred. Screen all pt for hepatitis B infection before initiating treatment….

F famciclovir fam-sye-klo-veer (Apo-Famciclovir , Famvir) Do not confuse Famvir with Femara. classification PHARMACOTHERAPEUTIC: Synthetic nucleoside. CLINICAL: Antiviral (see p. 70C). Action Inhibits viral DNA synthesis. Therapeutic Effect: Suppresses replication…

G gabapentin ga-ba-pen-tin (Apo-Gabapentin , Gralise, Horizant, Neurontin) Do not confuse Neurontin with Motrin, Neoral, nitrofurantoin, Noroxin, or Zarontin. classification PHARMACOTHERAPEUTIC: Gamma-aminobutyric acid analogue. CLINICAL: Anticonvulsant, antineuralgic (see p. 36C)….