CHAPTER 52 Anticoagulant, antiplatelet, and thrombolytic drugs COAGULATION: PHYSIOLOGY AND PATHOPHYSIOLOGY Hemostasis Thrombosis OVERVIEW OF DRUGS FOR THROMBOEMBOLIC DISORDERS ANTICOAGULANTS Heparin and Its Derivatives: Drugs That Activate Antithrombin Heparin (Unfractionated)…
CHAPTER 34 Sedative-hypnotic drugs Benzodiazepines Benzodiazepine-like Drugs Zolpidem Zaleplon Eszopiclone Ramelteon: A Melatonin Agonist Barbiturates Miscellaneous Sedative-Hypnotics Management of Insomnia Sleep Phases Basic Principles of Management Major Hypnotics Used for…
CHAPTER 47 Drugs for hypertension BASIC CONSIDERATIONS IN HYPERTENSION Classification of Blood Pressure Types of Hypertension Consequences of Hypertension MANAGEMENT OF CHRONIC HYPERTENSION Basic Considerations Lifestyle Modifications Drug Therapy Review…
CHAPTER 28 Opioid (narcotic) analgesics, opioid antagonists, and nonopioid centrally acting analgesics OPIOID ANALGESICS Introduction to the Opioids Terminology Endogenous Opioid Peptides Opioid Receptors Classification of Drugs That Act at…
CHAPTER 72 Glucocorticoids in nonendocrine disorders Review of Glucocorticoid Physiology Physiologic Effects Control of Synthesis and Secretion Pharmacology of the Glucocorticoids Molecular Mechanism of Action Pharmacologic Effects Pharmacokinetics Therapeutic Uses…
CHAPTER 29 Pain management in patients with cancer Pathophysiology of Pain Management Strategy Assessment and Ongoing Evaluation Comprehensive Initial Assessment Ongoing Evaluation Barriers to Assessment Drug Therapy Nonopioid Analgesics Opioid…
CHAPTER 4 Pharmacokinetics Application of Pharmacokinetics in Therapeutics A Note to Chemophobes Passage of Drugs Across Membranes Membrane Structure Three Ways to Cross a Cell Membrane Polar Molecules Ions Absorption…
CHAPTER 92 Antifungal agents Drugs for Systemic Mycoses Amphotericin B, a Polyene Antibiotic Azoles Echinocandins Flucytosine, a Pyrimidine Analog Drugs for Superficial Mycoses Overview of Drug Therapy Azoles Griseofulvin Polyene…
CHAPTER 103 Anticancer drugs II: hormonal agents, targeted drugs, and other noncytotoxic anticancer drugs DRUGS FOR BREAST CANCER Antiestrogens Aromatase Inhibitors Trastuzumab Lapatinib Cytotoxic Drugs (Chemotherapy) Denosumab and Bisphosphonates for…
CHAPTER 107 Miscellaneous noteworthy drugs Drugs for Pulmonary Arterial Hypertension Prostacyclin Analogs Endothelin-1 Receptor Antagonists Phosphodiesterase Type 5 Inhibitors Drugs for Neonatal Respiratory Distress Syndrome Prenatal and Postnatal Glucocorticoids Lung…
