Nurse Key

P paclitaxel pak-li-tak-sel (Abraxane, Apo-Paclitaxel ) BLACK BOX ALERT Myelosuppression is major dose-limiting toxicity. Must be administered by certified chemotherapy personnel. Severe hypersensitivity reactions reported. Do not confuse paclitaxel with…

A abacavir a-bak-a-veer (Ziagen) BLACK BOX ALERT Serious, sometimes fatal hypersensitivity reactions, lactic acidosis, severe hepatomegaly with steatosis (fatty liver) have occurred. Fixed-combination(s) Epzicom: abacavir/lamivudine (antiretroviral): 600 mg/300 mg. Trizivir:…

Z zafirlukast za-fir-loo-kast (Accolate) Do not confuse Accolate with Accupril, Accutane, or Aclovate. classification PHARMACOTHERAPEUTIC: Leukotriene receptor antagonist. CLINICAL: Antiasthma (see p. 78C). Action Binds to leukotriene receptors, inhibiting bronchoconstriction…

K ketoconazole kee-toe-kon-a-zol (Apo-Ketoconazole , Extina, Nizoral, Nizoral AD, Novo-Ketoconazole , Xolegel) BLACK BOX ALERT Potentially fatal hepatotoxicity has occurred. Concurrent cisapride, terfenadine, astemizole contraindicated; serious cardiovascular events (QT prolongation,…

Q quetiapine kwet-eye-a-peen (Apo-Quetiapine , Seroquel, Seroquel XR) BLACK BOX ALERT Increased risk of suicidal ideation and behavior in children, adolescents, young adults 18–24 yrs with major depressive disorder, other…

W warfarin war-far-in (Apo-Warfarin , Coumadin, Jantoven, Novo-Warfarin ) BLACK BOX ALERT May cause major or fatal bleeding. Risk factors include history of GI bleeding, hypertension, cerebrovascular disease, heart disease,…

O Obesity management Uses Adjunct to diet and physical activity in the treatment of chronic, relapsing obesity. Actions Two categories of medications are used for weight control. Appetite suppressants: Block…

H H2 antagonists Uses Short-term treatment of duodenal ulcer (DU), active benign gastric ulcer (GU), maintenance therapy of DU, pathologic hypersecretory conditions (e.g., Zollinger-Ellison syndrome), gastroesophageal reflux disease (GERD), and…

U ustekinumab yoo-ste-kin-ue-mab (Stelara) Do not confuse Stelara with Aldara, or ustekinumab with infliximab or rituximab. classification PHARMACOTHERAPEUTIC: Monoclonal antibody. CLINICAL: Antipsoriasis agent. Action Strongly binds with cellular components involved…

S Sedative-hypnotics Uses Treatment of insomnia (i.e., difficulty falling asleep initially, frequent awakening, awakening too early). Action Benzodiazepines are the most widely used agents and largely replace barbiturates due to…