Telmisartan

Telmisartan
(tell mah sar’ tan)
Micardis
PREGNANCY CATEGORY D
Drug Classes
Angiotensin II receptor antagonist
Antihypertensive
Therapeutic Actions
Selectively blocks the binding of angiotensin II to specific tissue receptors found in the vascular smooth muscle and adrenal gland; this action blocks the vasoconstriction effect of the renin-angiotensin system, as well as the release of aldosterone, leading to decreased BP.
Indications
  • Treatment of hypertension, alone or in combination with other antihypertensive
  • CV risk reduction, including risk of MI, stroke, or death, in patients 55 yr and older at high risk for developing major CV events who are unable to take ACE inhibitors
Available Forms
Tablets—20, 40, 80 mg
Dosages
Adults
Usual starting dose, 40 mg PO daily. Adjust dosage based on patient response. Range, 20–80 mg/day. If response is still not as expected, a diuretic may be added. For CV risk reduction, 80 mg PO once a day.
Pediatric patients
Safety and efficacy not established.
Pharmacokinetics
Route Onset Peak Duration
Oral Rapid 0.5–1 hr 24 hr

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Jul 21, 2016 | Posted by in NURSING | Comments Off on Telmisartan

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