Tamsulosin Hydrochloride(tam soo low’ sin)
FlomaxDNC
PREGNANCY CATEGORY B
Drug class
Alpha-adrenergic blocker (peripherally acting)
Therapeutic Actions
Blocks the smooth muscle alpha1-adrenergic receptors in the prostate, prostatic capsule, prostatic urethra, and bladder neck, leading to relaxation of the bladder and prostate and improving the flow of urine in cases of BPH, with little effect on systemic blood pressure.
Indications
Treatment of the signs and symptoms of BPH
Unlabeled use: Adjunct in managing ureteral stones
Contraindications and Cautions
Contraindicated with hypersensitivity to tamsulosin, prostate cancer, pregnancy, lactation.
Use cautiously with hypotension, sulfa hypersensitivity.
Available Forms
CapsulesDNC—0.4 mg
Dosages
Adults
0.4 mg PO daily 30 min after the same meal each day; if response is not satisfactory in 2–4 wk, dosage may be increased to 0.8 mg PO daily 30 min after the same meal each day. If therapy is interrupted for any reason for several days, resume dosing at 0.4 mg PO daily.
Pediatric patients
Safety and efficacy not established.
Pharmacokinetics
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