Reviewing the techniques
his left side; this movement may cause the heart to shift closer to the chest wall. Note the rate and quality of the apical pulse.
limited. Use the following teaching tips as a guide.
position, with one hand placed on his chest and the other hand placed over his upper abdomen. Instruct him to exhale normally, close his mouth, and inhale deeply through his nose. His chest shouldn’t expand. Ask him to hold his breath and slowly count to five. Next, ask him to purse his lips and exhale completely through his mouth, without letting his cheeks expand. Tell the patient to repeat the exercise 5 to 10 times.
DRUG | POSSIBLE EFFECT |
Antianxiety drugs | |
diazepam Valium | ♦ Excessive sedation ♦ Preoperative or postoperative nausea and vomiting ♦ Local tissue irritation (with I.V. administration) |
hydroxyzine hydrochloride Vistaril | ♦ Drowsiness and dry mouth |
midazolam hydrochloride | ♦ Respiratory depression (with high doses) |
Antiarrhythmics | |
All types | ♦ Laryngospasm ♦ Intensified cardiac depression and reduced cardiac output |
procainamide | ♦ Prolonged or enhanced effects of neuromuscular blockers ♦ Hypotension |
propranolol Inderal | ♦ Prolonged or enhanced effects of neuromuscular blockers ♦ Depressed myocardial function ♦ Hypotension ♦ Laryngospasm |
Antibiotics | |
All types | ♦ Masked symptoms of infection |
Aminoglycosides amikacin, gentamicin, kanamycin, neomycin, streptomycin, tobramycin | ♦ Increased risk of neuromuscular blockade and respiratory paralysis |
erythromycin Erythrocin, E-Mycin | ♦ Prolonged action of opiates |
Anticholinergics | |
atropine sulfate | ♦ Excessive dryness of the mouth, tachycardia, flushing, and decreased sweating ♦ Increased intraocular pressure (IOP), blurred vision, and dilated pupils ♦ Urine retention ♦ Agitation and delirium (in elderly patients) |
glycopyrrolate Robinul | ♦ Excessive dryness of the mouth, tachycardia, flushing, and decreased sweating ♦ Increased IOP, blurred vision, and dilated pupils ♦ Urine retention |
scopolamine bromide | ♦ Excessive dryness of the mouth, tachycardia, and flushing ♦ Increased IOP, blurred vision, and dilated pupils ♦ Urine retention ♦ Excessive drowsiness ♦ Agitation and delirium (in elderly patients) |
Anticoagulants | |
heparin sodium warfarin Coumadin | ♦ Increased risk of hemorrhage |
Anticonvulsants | |
magnesium sulfate | ♦ Increased risk of neuromuscular blockade |
Antidiabetics | |
insulin | ♦ Increased insulin requirement during stress and healing ♦ Decreased insulin requirement during fasting |
Antihypertensives | |
All types | ♦ Worsened hypotension |
Central nervous system depressants | |
Alcohol, sedative hypnotics | ♦ If given with general anesthetics, increased risk of respiratory depression, apnea, or hypotension |
Corticosteroids | |
betamethasone, cortisone, dexamethasone, hydrocortisone, methylprednisolone, prednisolone, prednisone, triamcinolone | ♦ Delayed wound healing ♦ Risk of acute adrenal insufficiency ♦ Increased risk of infection ♦ Masked symptoms of infection ♦ Increased risk of hemorrhage |
Diuretics | |
furosemide Lasix Potassium-wasting diuretics | ♦ If given with certain anesthetics, increased risk of hypotension ♦ Increased risk of complications associated with hypokalemia |
Histamine-2 receptor antagonists | |
cimetidine Tagamet ranitidine Zantac | ♦ Decreased clearance of all drugs, especially diazepam, lidocaine, and propranolol |
Myotics | |
demecarium, echothiophate, isoflurophate | ♦ If given with succinylcholine, increased risk of neuromuscular blockade, cardiovascular collapse, prolonged respiratory depression, or apnea (effects may occur up to a few months after the patient stops taking the drug) |
Nonsteroidal anti-inflammatory drugs | |
celecoxib, ibuprofen, meloxicam, naproxen, rofecoxib | ♦ Increased risk of bleeding or hemorrhage |
Opiates | |
All types | ♦ If given with certain I.V. anesthetics (such as midazolam, propofol, thiopental, and droperidol), increased risk of respiratory depression, apnea, or hypotension |
Opioids | |
meperidine hydrochloride morphine Demerol | ♦ Depressed respiration, circulation, and gastric motility ♦ Dizziness, tachycardia, and sweating ♦ Hypotension, restlessness, and excitement ♦ Preoperative or postoperative nausea and vomiting |
Sedative-hypnotics | |
pentobarbital sodium Nembutal | ♦ Confusion or excitement, especially in elderly patients or patients with severe pain |
Thyroid hormones | |
All types | ♦ If given with ketamine, increased risk of hypertension and tachycardia |
Tranquilizers | |
promethazine hydrochloride Phenergan | ♦ Postoperative hypotension |