Figure 95.1 Signs of septicaemia Note: Hypotension is a late sign in children and indicates decompensated shock Septicaemia is defined as the presence of numerous bacteria in the blood that are actively dividing. This results in a systemic response to the infection leading to organ dysfunction. It can be complicated by circulatory collapse, myocardial depression, increased metabolic rate and perfusion abnormalities. Systemic inflammatory response syndrome (SIRS): two of the following four criteria present: Sepsis:
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