CHAPTER 12 After reading this chapter, you should be able to do the following: • Identify the purpose of sampling. • Define population, sample, and sampling. • Compare a population and a sample. • Discuss the importance of inclusion and exclusion criteria. • Define nonprobability and probability sampling. • Identify the types of nonprobability and probability sampling strategies. • Compare the advantages and disadvantages of nonprobability and probability sampling strategies. • Discuss the contribution of nonprobability and probability sampling strategies to strength of evidence provided by study findings. • Discuss the factors that influence determination of sample size. • Discuss potential threats to internal and external validity as sources of sampling bias. • Use the critiquing criteria to evaluate the “Sample” section of a research report. Go to Evolve at http://evolve.elsevier.com/LoBiondo/ for review questions, critiquing exercises, and additional research articles for practice in reviewing and critiquing. When you are critically appraising the sampling section of a study, the threats to internal and external validity as sources of bias need to be considered (see Chapter 8). Your evaluation of the sampling section of a study is very important in your overall critical appraisal of a study’s findings and their applicability to practice. This chapter will familiarize you with the basic concepts of sampling as they primarily pertain to the principles of quantitative research design, nonprobability and probability sampling, sample size, and the related appraisal process. Sampling issues that relate to qualitative research designs are discussed in Chapters 5, 6, and 7. Think about the concept of inclusion or eligibility criteria applied to a study where the subjects are patients. For example, participants in a study investigating the effectiveness of a motivational-interviewing–based coaching intervention compared to usual care to improve cancer pain management (Thomas et al., 2012; see Appendix A) had to meet the following inclusion (eligibility) criteria: 2. Pain Intensity Status: pain intensity score of 2 or higher on a scale of 0-10 3. Health status: life expectancy longer than 6 months 4. Available resources: access to a telephone • A concurrent cognitive or psychiatric condition or substance abuse problem that would prevent adherence to the protocol • Severe pain unrelated to their cancer • A housing setting where the patient could not self-administer pain medication (e.g., skilled nursing facility) The careful establishment of sample inclusion or exclusion criteria will increase the study’s precision and strength of evidence, thereby contributing to the accuracy and generalizability of the findings (see Chapter 8). The purpose of sampling is to increase a study’s efficiency. As a new evaluator of research you must realize that it would not be feasible to examine every element in the population. When sampling is done properly, the researcher can draw inferences and make generalizations about the population without examining each element in the population. Sampling procedures that formulate specific criteria for selection ensure that the characteristics of the phenomena of interest will be, or are likely to be, present in all of the units being studied. The researcher’s efforts to ensure that the sample is representative of the target population strengthens the evidence generated by the sample composition, which puts the researcher in a stronger position to draw conclusions that are generalizable to the population and applicable to practice (see Chapter 8). Probability sampling uses some form of random selection when the sample is chosen. This type of sample enables the researcher to estimate the probability that each element of the population will be included in the sample. Probability sampling is the more rigorous type of sampling strategy and is more likely to result in a representative sample. The remainder of this section is devoted to a discussion of different types of nonprobability and probability sampling strategies. A summary of sampling strategies appears in Table 12-1. You may wish to refer to this table as the various nonprobability and probability strategies are discussed in the following sections. TABLE 12-1 SUMMARY OF SAMPLING STRATEGIES Convenience sampling is the use of the most readily accessible persons or objects as subjects. The subjects may include volunteers, the first 100 patients admitted to hospital X with a particular diagnosis, all of the people enrolled in program Y during the month of September, or all of the students enrolled in course Z at a particular university during 2014. The subjects are convenient and accessible to the researcher and are thus called a convenience sample. For example, a researcher studying the relationship among maternal-fetal attachment (MFA), health practices during pregnancy, and neonatal outcomes in a sample of low-income predominantly African-American women and their neonates recruited a convenience sample of 167 women from three urban obstetrical clinics in the Mid Atlantic region who met the eligibility criteria and volunteered to participate in the study (Alhusen et al., 2012; see Appendix B). The advantage of a convenience sample is that generally it is easier for the researcher to obtain subjects. The researcher may have to be concerned only with obtaining a sufficient number of subjects who meet the same criteria. A convenience sample may be the most appropriate sampling strategy to use even though it is not the strongest approach. The major disadvantage of a convenience sample is that the risk of bias is greater than in any other type of sample (see Table 12-1). The fact that convenience samples use voluntary participation increases the probability of researchers recruiting those people who feel strongly about the issue being studied, which may favor certain outcomes (Sousa et al., 2004). In this case, you can ask yourself the following as you think about the strength and quality of evidence contributed by the sampling component of a study: • What motivated some people to participate and others not to participate (self-selection)? • What kind of data would have been obtained if nonparticipants had also responded? • How representative are the people who did participate in relation to the population? • What kind of confidence can you have in the evidence provided by the findings? Researchers may recruit subjects when they stop people on a street corner to ask their opinion on some issue, place advertisements in the newspaper, or place signs in local churches, community centers, or supermarkets indicating that volunteers are needed for a particular study. To assess the degree to which a convenience sample approximates a random sample, the researcher checks for the representativeness of the convenience sample by comparing the sample to population percentages and, in that way, assesses the extent to which bias is or is not evident (Sousa et al., 2004). Because acquiring research subjects is a problem that confronts many nurse researchers, innovative recruitment strategies may be used. A unique method of accessing and recruiting subjects is the use of online computer networks (e.g., disease-specific chat rooms, blogs, and bulletin boards). In the evidence hierarchy in Figure 1-1, nonprobability sampling is most commonly associated with quantitative nonexperimental or qualitative studies that contribute Level IV through Level VI evidence. When you appraise a study you should recognize that the convenience sample strategy, although the most common, is the weakest sampling strategy with regard to strength of evidence and generalizability. When a convenience sample is used, caution should be exercised in interpreting the data. When critiquing a study that has employed this sampling strategy, the reviewer should be justifiably skeptical about the external validity and applicability of the findings (see Chapter 8). Quota sampling refers to a form of nonprobability sampling in which knowledge about the population of interest is used to build some representativeness into the sample (see Table 12-1). A quota sample identifies the strata of the population and proportionally represents the strata in the sample. For example, the data in Table 12-2 reveal that 40% of the 5000 nurses in city X are associate degree graduates, 30% are 4-year baccalaureate degree graduates, and 30% are accelerated baccalaureate graduates. Each stratum of the population should be proportionately represented in the sample. In this case, the researcher used a proportional quota sampling strategy and decided to sample 10% of a population of 5000 (i.e., 500 nurses). Based on the proportion of each stratum in the population, 400 associate degree graduates, 300 4-year baccalaureate graduates, and 300 accelerated baccalaureate graduates were the quotas established for the three strata. The researcher recruited subjects who met the study’s eligibility criteria until the quota for each stratum was filled. In other words, once the researcher obtained the necessary 400 associate degree graduates, 300 4-year baccalaureate degree graduates, and 300 accelerated baccalaureate degree graduates, the sample was complete. TABLE 12-2 NUMBERS AND PERCENTAGES OF STUDENTS IN STRATA OF A QUOTA SAMPLE OF 5,000 GRADUATES OF NURSING PROGRAMS IN CITY X
Sampling
Sampling concepts
Population
Inclusion and exclusion criteria
Samples and sampling
Types of samples
SAMPLING STRATEGY
EASE OF DRAWING SAMPLE
RISK OF BIAS
REPRESENTATIVENESS OF SAMPLE
NONPROBABILITY
Convenience
Easy
Greater than any other sampling strategy
Because samples tend to be self-selecting, representativeness is questionable
Quota
Relatively easy
Contains unknown source of bias that affects external validity
Builds in some representativeness by using knowledge about population of interest
Purposive
Relatively easy
Bias increases with greater heterogeneity of population; conscious bias is also a danger
Very limited ability to generalize because sample is handpicked
PROBABILITY
Simple random
Time consuming
Low
Maximized; probability of nonrepresentativeness decreases with increased sample size
Stratified random
Time consuming
Low
Enhanced
Cluster
Less or more time consuming depending on the strata
Subject to more sampling errors than simple or stratified
Less representative than simple or stratified
Nonprobability sampling
Convenience sampling
Quota sampling
ASSOCIATE DEGREE GRADUATES
4-YEAR BACCALAUREATE DEGREE GRADUATES
ACCELERATED BACCALAUREATE DEGREE GRADUATES
Population
2,000 (40%)
1,500 (30%)
1,500 (30%)
Strata
200
150
150
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