Rotigotine(roe tig oh teen)
Neupro
PREGNANCY CATEGORY C
Drug Classes
Antiparkinsonian
Dopamine agonist
Therapeutic Actions
Dopamine agonist; stimulates dopamine receptors within the caudate putamen in the brain, which relieves some of the signs and symptoms of Parkinson disease. Restless legs syndrome is thought to be related to inability to stimulate dopamine receptors in this area of the brain.
Indications
Treatment of signs and symptoms of Parkinson disease
Treatment of moderate to severe restless legs syndrome
Contraindications and Cautions
Contraindicated with history of serious hypersensitivity reactions to component of the drug or sulfites (components of the transdermal patch)
Use cautiously with hypotension, lactation, pregnancy.
Available Forms
Transdermal patch—1, 2, 3, 4, 6, 8 mg/24 hr
Dosages
Adults
Parkinson disease: 2-mg/24-hr transdermal patch for early stage disease to 4-mg/24-hr transdermal patch for advanced disease; may increase to a maximum 6-mg/24-hr transdermal patch for early stage disease or 8-mg/24-hr transdermal patch for advanced disease.
Restless legs syndrome: 1-mg/24-hr transdermal patch up to a maximum 3-mg/24-hr transdermal patch as needed
Pharmacokinetics
|
Stay updated, free articles. Join our Telegram channel
Full access? Get Clinical Tree
