Pravastatin Sodium



Pravastatin Sodium





(prah va sta’ tin)

Apo-Pravastatin (CAN), CO Pravastatin (CAN), Gen-Pravastatin (CAN), Novo-Pravastatin (CAN), Nu-Pravastatin (CAN), PMS-Pravastatin (CAN), Pravachol, ratio-Pravastatin (CAN)

PREGNANCY CATEGORY X


Drug Classes

Antihyperlipidemic

HMG-CoA reductase inhibitor


Therapeutic Actions

Inhibits the enzyme HMG-CoA that catalyzes the first step in the cholesterol synthesis pathway, resulting in a decrease in serum cholesterol, serum LDLs (associated with increased risk of CAD), and either an increase or no change in serum HDLs (associated with decreased risk of CAD).


Indications



  • Prevention of first MI and reduction of death from CV disease in patients with hypercholesterolemia at risk of first MI


  • Adjunct to diet in the treatment of elevated total cholesterol and LDL cholesterol with primary hypercholesterolemia (types IIa and IIb) in patients unresponsive to dietary restriction of saturated fat and cholesterol and other nonpharmacologic measures


  • Slow the progression of coronary atherosclerosis in patients with clinically evident CAD to reduce the risk of acute coronary events and revascularization procedures in hypercholesterolemia patients


  • Reduce the risk of stroke or TIA in patients with history of MI and normal cholesterol levels


  • Reduce the risk of recurrent MI and death from heart disease in patients with history of MI and normal cholesterol levels


  • Treatment of children 8 yr and older with heterozygous familial hypercholesterolemia as an adjunct to diet and exercise


Jul 21, 2016 | Posted by in NURSING | Comments Off on Pravastatin Sodium

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