Chapter 12 Ann L. Bevan This chapter explores the role of the digestive system as it removes nutrients from the food that a child eats to enable growth and development, and the changes that can occur when pathology is disturbed. The gastrointestinal system includes the mouth, pharynx, oesophagus, stomach and intestines, ending at the anus; in total it measures approximately 10 metres in length. Supporting structures include accessory organs necessary for digestion, such as salivary glands, liver, pancreas and gallbladders. The function of the gastrointestinal tract is to digest and absorb nutrients and then eliminate waste products. In this chapter some of the most common gastrointestinal disorders in infants, children and young people will be presented. Nursing care of the infant, child or young person and management of these disorders will be considered within the context of a family‐centred approach to care. The chapter is organised under the main headings of motility disorders, inflammatory conditions, obstructive disorders, malabsorption disorders, structural defects, and hernias. Motility disorders include all those affecting the normal movement of matter through the GI system. Any condition that slows or speeds the movement of matter through the GI system alters the absorption rate of fluids and nutrients. Symptoms may include diarrhoea and vomiting, resulting in fluid and electrolyte disturbances. Gastroenteritis is an acute or chronic inflammation of the stomach and intestines often accompanied by vomiting and diarrhoea. It can affect any part of the gastrointestinal tract and may be caused by a viral, bacterial or parasitic infection. This condition is common in children under 5 years who on average experience two episodes per year with rotavirus being the most common cause in this age group (Ball, Bindler & Cowen, 2015). Frequent episodes of diarrhoea, especially if accompanied by vomiting, can lead to severe dehydration in infants and young children putting them at risk for hypovolemic shock if fluid and electrolytes are not replaced. This may necessitate a hospital admission for intravenous fluids. Diarrhoea can be acute or chronic. Acute diarrhoea is defined as a sudden increase in frequency and change in consistency of stools often caused by an infection. This is usually self‐limiting and may or may not be severe enough to cause dehydration. Chronic diarrhoea occurs over more than 14 days and is often caused by chronic conditions, such as inflammatory bowel disease (IBD), malabsorption syndromes, food allergies or non‐specific causes. Causes of acute and chronic diarrhoea are presented in Table 12.1. Table 12.1 Possible causes of acute and chronic diarrhoea Diarrhoea can be mild, moderate, or severe. This is determined by the number of stools and how liquid they are. In addition, the severity of other accompanying symptoms, such as irritability, anorexia, nausea and vomiting and electrolyte imbalance, determine the severity and subsequent treatment. Diagnosis is based on history, physical examination, and laboratory results. A thorough history should include questions about recent travel, day‐care attendance and recent medications or dietary changes. Questions should also be asked about the frequency and character of stools, urinary output and intake of food and fluids, and the presence of fever or vomiting. Physical examination gives an indication of the severity of the dehydration. Laboratory evaluation of blood and urine gives an indication of electrolyte imbalance, and stools can be examined for the presence of infectious organisms, viruses, parasites, ova, fat and undigested sugars. Medical management depends on the severity of the diarrhoea and dehydration. Rehydration with an intravenous solution chosen to correct the specific dehydration will be used in those children with severe diarrhoea and accompanying dehydration. Clear oral fluids or breast milk will be introduced as soon as possible and then progression to normal diet. If the diarrhoea is caused by bacteria or parasites, antibiotics may be prescribed. Constipation is a common problem in childhood; depending on the criteria used to diagnose the condition, the prevalence may be as high as 30%, and in one‐third of those the condition becomes chronic (NICE, 2010). The cause of constipation may be dietary, an underlying disease or as a result of psychological factors, or it may be idiopathic and therefore have no known cause. It may also be as a result of defects in filling or emptying of the rectum, such as in Hirschsprung disease, stricture or stenosis. Constipation in infancy is uncommon and most often associated with changes of diet, such as from breastfeeding to cow’s milk due to the protein content. The most common time for the condition is during toddler and childhood years when withholding of stool may be the cause because of the unpleasant sensations associated with defecating. In the older child it is more commonly associated with lack of fibre in the diet and a sedentary lifestyle. Children and young people with physical disabilities and associated impaired mobility are more prone to constipation. Signs and symptoms may include: abdominal pain, abdominal distension, hard painful stools, a decrease in stool frequency, excessive flatulence, lack of appetite, general malaise, constipation with faecal soiling (encopresis), and irritability. Diagnosis is made on a thorough history of stool frequency and consistency, and a physical examination. Early diagnosis and treatment of an acute episode of constipation is important in order to prevent the condition becoming chronic. Early identification of constipation and effective treatment can improve outcomes for children and young people (NICE, 2010). The first line of treatment for constipation that has no underlying pathological cause is dietary management. However, for children with impacted faeces an enema and/or laxatives will be administered, accompanied by both behavioural interventions and dietary modification to ensure a balanced diet and adequate fluid intake. The goals for management are to restore and maintain regular toileting routines and evacuation of stool. Nursing care focuses on teaching patents about normal bowel patterns in children and the appearance of a normal stool. Families need reassurance that establishing normal patterns can take time and they need to be persistent and consistent, and provide the child with positive reinforcement. Vomiting is one of the most common symptoms in childhood. In infants it is normal to regurgitate small amounts of milk, called posseting, but in childhood it is often due to gastroenteritis. It may also be associated with other conditions, see Table 12.2 for some of the causes. The history of vomiting and associated symptoms may help to identify the cause. Vomiting in childhood is usually self‐limiting with no treatment required; however, complications can occur and these may include: dehydration, electrolyte imbalances, aspiration or malnutrition. Table 12.2 Possible causes of vomiting The vomiting reflex is under the central nervous system control, specifically the medulla. Nausea, meaning the desire to vomit, is a sensation that may be induced by a number of causes including inner ear, visceral or emotional stimuli. It may lead to retching due to contraction of the abdominal muscles. A thorough history should be taken to ascertain the underlying cause alongside a physical examination to identify any abdominal pain or dehydration. The type of vomitus and its relation to meals or specific foods, behaviour and any accompanying pain need to be ascertained. It is also important to assess for the presence of constipation, diarrhoea or jaundice. Other causes, such as urinary infections, brain tumour, and any anatomic abnormalities, need to be ruled out with diagnostic tests, such as blood and urine analysis, X‐ray, and brain scan. If a cyclic vomiting pattern is present, it may indicate an eating disorder such as bulimia, and therefore a psychiatric assessment may be needed. If the vomiting persists for more than 24 hours, parenteral fluids may need to be considered in order to correct or prevent dehydration. Anti‐emetic drugs are usually only administered in cases of extensive post‐operative vomiting, chemotherapy‐induced vomiting, or for travel sickness. Nursing care is determined by the cause of the vomiting but in general includes observing the type of vomit, placing the infant or child who is vomiting in a position to prevent aspiration, cleaning the mouth after vomiting to prevent the acid damaging teeth, assessing for dehydration, carrying out routine observations and encouraging small amounts of fluid regularly when tolerated. Once vomiting has ceased, fluids and small amounts of diet can be encouraged. Gastro‐oesophageal reflux (GOR) refers to the return of gastric contents into the oesophagus, and is a common symptom affecting 40% of infants and young children (NICE, 2015a). The cause of GOR is a poorly functioning gastro‐oesophageal sphincter, which normally prevents stomach contents from regurgitating back into the oesophagus. Some positing of milk is considered normal in newborns following a feed; however, regurgitation that continues or increases requires further investigation. Infants with reflux are at risk of aspiration and apnoea, particularly if lying down. GOR usually begins before the infant is 8 weeks old and may occur several times a day, but this lessens in frequency over time. It is important to reassure parents that in well infants, with no symptoms other than effortless regurgitation, 90% of cases usually resolve before they are 1 year old and do not require further investigation (NICE, 2015a). There is an increased prevalence of GOR in premature infants, children or young people with obesity, hiatus hernia, diaphragmatic hernia or oesophageal atresia repair, and children with a neuro‐disability. Other symptoms include heartburn, regurgitation, epigastric and retrosternal pain, and weight loss, and most sufferers are irritable. Infants with GOR, particularly premature infants, are at risk for aspiration and apnoea. Diagnosis is made on the symptoms and an upper GI contrast study for those with persistent or recurring symptoms. In infants with unexplained bile‐stained vomiting, an upper GI contrast study will be done urgently in order to rule out more serious disorders, such as intestinal obstruction (NICE, 2015a). Treatment depends on the severity and cause of GOR. Initially in infants, feeding with thickened feeds and upright positioning may be enough for milder cases. Feeding smaller amounts more often may help to reduce abdominal distension and associated reflux. Frequent winding throughout a feed also helps to prevent the build‐up of abdominal wind associated with feeding. Depending on the healthcare provider, pharmacological treatment may be administered; this would depend on the cause of the problem and the severity. In some cases where there is failure to thrive or persistent weight loss enteral tube feeding may be considered. Surgery for GOR is only performed when medical therapy has failed and complications develop (see Table 12.3). Table 12.3 Possible complications of gastro‐oesophageal reflux (GOR) Source: NICE 2015a. Nursing management focuses on ensuring the infant or child receives adequate nutrition. Daily weights and plotting infant or child weight and height on a percentile chart will monitor growth. Sandifer syndrome is the abnormal posturing that may occur in cases of severe acid reflux and may be mistakenly diagnosed as a seizure. Hirschsprung disease (congenital aganglionic megacolon) is a congenital anomaly that causes inadequate motility due to the absence of parasympathetic ganglion cells in the affected areas of the intestine, mostly the recto‐sigmoid region of the colon. This lack of motility leads to mechanical obstruction of the intestine and a distended sigmoid colon. The incidence is 1 in 5000 live births and is more common in males than females (Ball et al., 2015); in many cases it has a familial pattern. The age of onset will determine the clinical manifestations of the disease. In newborn infants there may be a failure to pass meconium in the first 48 hours, abdominal distension, feeding intolerance and bilious vomiting. In the older infant or child there may be a history of ribbon‐like foul‐smelling stools, visible peristalsis, easily palpable faecal mass, failure to thrive, chronic progressive constipation, which may be accompanied by episodes of faecal impaction. Diagnosis is made on the history and physical examination. An abdominal X‐ray will show the distended colon and a lack of stool in the rectum. A rectal biopsy will be performed to confirm the absence of ganglion cells. Treatment is to remove the aganglionic portion of the bowel and a procedure consisting of pulling through the normal bowel to the end of the rectum to replace the removed portion. If the area of colon affected is too large for an immediate pull‐through or it is inflamed, a temporary colostomy may be created and surgery performed later. Following the pull‐through procedure incontinence and stricture may occur, requiring dilations or bowel retraining. Surgery is usually delayed in infants until they are 10 months old. Nursing care is focused around observing for infection and ensuring adequate nutrition, maintaining hydration, pain management and providing support to the child and family. One very serious complication in infancy is enterocolitis, which can be fatal if not recognised early. Following a pull‐through operation it is important to monitor the return of bowel function. If a colostomy is performed, post‐operative stoma care and parent and child education in the care of a stoma will be needed. Inflammatory disorders may be acute or chronic and be anywhere in the gastrointestinal tract. Causes may include injuries, foreign bodies, surgery, micro‐organisms or chemicals. Included here are appendicitis and inflammatory bowel disease. Appendicitis is an inflammation of the vermiform appendix, which is a blind sac located near the end of the caecum. Appendicitis is the most common cause of acute abdominal surgery in children and can occur at any age although it is most often seen in children over 5 years with a peak incidence at 10 years (Ball et al., 2015; Hockenberry & Wilson, 2015). Appendicitis results from an obstruction in lumen of the appendix usually by a faecalith, which is a hardened faecal mass. It can also be caused by a parasitic infestation, stenosis lymphoid tissue or a tumour. The tissue becomes swollen due to the continuing production of mucus secretions causing build‐up and pressure within the lumen, which results in compression of blood vessels. This compression can lead to ischaemia, tissue death and necrosis. The appendix may perforate or rupture allowing faecal matter and bacteria to be released into the peritoneal cavity. This then spreads rapidly throughout the abdomen causing peritonitis. Progressive peritoneal infection can lead to small bowel obstruction, septicaemia, electrolyte imbalance and hypovolaemic shock. Early abdominal symptoms of appendicitis include tenderness, colicky cramping pain around the umbilicus, anorexia, nausea and fever. The pain experienced around the umbilicus is known as referred pain. Focal abdominal tenderness occurs at the site of McBurney’s point, which is located two‐thirds along the line between the umbilicus and the left antero‐superior iliac spine (see Fig. 12.2). Rebound tenderness, guarding and rigidity may also be present.
Disorders of the digestive system
Aim
Introduction
Motility disorders
Gastroenteritis (diarrhoea)
Acute diarrhoea
Chronic diarrhoea
Constipation
Vomiting
Newborns and infants
Older children and adolescents
Gastro‐oesophageal reflux
Hirschsprung disease (Fig. 12.1)
Inflammatory conditions
Appendicitis