6 Dementia and delirium
Introduction
In the region of 60% of hospital patients will have pre-existing mental health problems or will develop one during their hospital stay; 80% of these individuals will have delirium, dementia or depression (Nursing and Midwifery Council (NMC) 2010). Delirium and dementia are two significant cognitive disorders that have overlapping characteristics which can make a definitive diagnosis difficult in the acute hospital setting.
As the population of older people with dementia is estimated to rise from 600 000 to 840 000 by 2026, and reach 1.2 million by 2050 (Alzheimer’s Society 1998), the need to improve diagnosis and implement prompt appropriate interventions is essential, as these patients are known to have higher mortality rates than patients with no cognitive disorder.
Delirium
Delirium is an acute disorder of the mental processes. It is not a disease, but a set of symptoms that are the result of an underlying health problem. Delirium can appear in varying degrees of intensity, and it occurs when brain activity is affected. Patients can suffer from hyperactive delirium and become agitated, restless and may be aggressive. Hypoactive delirium is when they are quiet and withdrawn, and mixed delirium is when patients display both behaviours. However, people with hypoactive delirium may not be recognised by staff (Flick et al 2007).
Delirium is a common problem in acutely ill older adults. In the region of 20–30% of people on medical wards and 10–50% of people having surgery develop delirium (National Institute for Health and Clinical Excellence (NICE) 2010). If your placement is classed as one of these types of learning environment, you may well meet a patient who has this problem.
Delirium is formally defined as a diagnosis in the Diagnosis and Statistical Manual of Mental Health Disorders, version 4 (DSM-IV 2000). As you will see, it is a complex condition to diagnose with a lot of conditional attributes, thus the diagnosis includes guidance on detection rather than just a definition and characteristics (see Box 6.1).
Box 6.1 Delirium: definition and examples
A. Disturbance of consciousness (i.e. reduced clarity of awareness of the environment) with reduced ability to focus, sustain or shift attention
B. A change in cognition (such as memory deficit, disorientation, language disturbance) or the development of a perceptual disturbance that is not better accounted for by a pre-existing, established or evolving dementia
C. The disturbance develops over a short period of time (usually hours to days) and tends to fluctuate during the course of the day
D. There is evidence from the history, physical examination or laboratory findings of the following:
The signs and symptoms of delirium, summarised in Box 6.2, are important to recognise because, if untreated, delirium can trigger the onset of chronic confusion (dementia) and result in nursing home placement. The important point to make is that these signs and symptoms have had a rapid onset so listening to family members is really important in ascertaining if the symptoms are new or related to existing dementia.
Box 6.2 Delirium: signs and symptoms
Symptoms of delirium generally fluctuate throughout the day and include the following:
Difficulty focusing, sustaining or shifting attention
Memory impairment, particularly recent memory
Disturbance of the sleep–wake cycle, for example drowsy during the day and agitated or restless at night
Speech or language disturbances, e.g. rambling speech
Disorientation to place or time
Disturbance in psychomotor behaviour
Agitation with increased psychomotor behaviour
Sluggishness with decreased psychomotor behaviour
Emotional disturbances – mood swings over the course of a day
Assessment of delirium
Without careful assessment, delirium can be confused with conditions such as dementia, depression and psychosis. Therefore, a thorough assessment is required, which should include a comprehensive history and in-depth assessment to confirm diagnosis (NICE 2010). A physical examination should also be undertaken to identify the cause: a range of blood tests (liver and renal function, electrolytes, blood count, serum calcium and glucose), urinalysis, chest X-ray, oxygen saturation and electrocardiogram will be required to determine the underlying cause. Medication should be assessed and, as required, amendments to prescriptions to minimise the effects of drug toxicity. Symptoms will subside as the underlying cause is addressed.
Some patients are more susceptible to delirium. Older people over 70 years of age, those with hearing and vision impairment and some cognitive impairment are at greatest risk. For these people, the onset of a severe medical illness, sleep deprivation for any reason, increased immobility and falls, dehydration and incontinence increase the risk of delirium. In fact, when an older person exhibits symptoms of delirium then immediate assessment for one or more of these treatable conditions should be carried out. A simple mnemonic to remember the key risk factors ofdelirium is PINCHME as shown in Box 6.3 (European Delirium Association 2010).
Nursing actions
Involve the family in the planning and provision of aspects of personal care, assisting with meals and giving drinks. Control the environment by reducing noise and bright lights and use large print and picture signage. Avoid moving the patient between wards and rooms (NICE 2010) and provide consistent care given by a limited number of people. Boxes 6.4 and 6.5 identify some key environmental and clinical strategies for managing delirium in hospital summarised from the European Delirium Association Website.
Box 6.4 Environmental strategies for delirium prevention and management
Lighting appropriate to time of day
Quiet environment especially at rest times – noise reduction strategies (e.g. use of vibrating pagers rather than call bells)
Clock and calendar that clients can see
Encourage family and carer involvement/visits
Encourage family/carer to bring in client’s personal and familiar objects
Box 6.5 Clinical strategies for delirium prevention and management
Ensure adequate intake of food and fluids
Hearing and visual aids available and used
Encourage and assist with mobilisation
Encourage independence in basic activities of daily living
Promote relaxation and sufficient sleep
Provide orienting information including name and role of staff members
Minimise use of indwelling catheters