Acamprosate Calcium (a kam pro’ sate) Campral PREGNANCY CATEGORY C Drug Classes Antialcoholic drug GABA analogue Therapeutic Actions Exact mechanism of action not understood; acts with glutamate and GABA neurotransmitter…

Abiraterone

Abciximab (ab six’ ah mab) ReoPro PREGNANCY CATEGORY C Drug Classes Antiplatelet Glycoprotein IIb/IIIa inhibitor Therapeutic Actions Interferes with platelet membrane function by inhibiting fibrinogen binding and platelet–platelet interactions; inhibits…

Abatacept

Abacavir Sulfate (ah bak’ ah veer) Ziagen PREGNANCY CATEGORY C Drug Classes Antiviral Nucleoside reverse transcriptase inhibitor Therapeutic Actions Nucleoside reverse transcriptase inhibitor; obstructs RNA and DNA synthesis and inhibits…

Tricyclic Antidepressants (TCAs) PREGNANCY CATEGORY C OR D (AMITRIPTYLINE, IMIPRAMINE, NORTRIPTYLINE) Therapeutic Actions Mechanism of action is unknown. The TCAs are structurally related to the phenothiazine antipsychotic drugs (eg, chlorpromazine),…

Tetracyclines PREGNANCY CATEGORY D Therapeutic Actions Tetracyclines are antibiotics. They are bacteriostatic; inhibit protein synthesis of susceptible bacteria, preventing cell replication. Indications Treatment of infections caused by rickettsiae; Mycoplasma pneumoniae;…

Sulfonamides PREGNANCY CATEGORY C PREGNANCY CATEGORY D (AT TERM) Therapeutic Actions Sulfonamides are antibiotics. They are bacteriostatic; competitively antagonize para-aminobenzoic acid, an essential component of folic acid synthesis, in susceptible…

Selective Serotonin Reuptake Inhibitors (SSRIs) PREGNANCY CATEGORY C Therapeutic Actions The SSRIs act as antidepressants by inhibiting CNS neuronal uptake of serotonin with little or no effect on norepinephrine; they…

Phosphodiesterase Type 5 Inhibitors PREGNANCY CATEGORY B Therapeutic Actions Selectively inhibits cGMP-specific phosphodiesterase type 5. The mechanism of penile erection involves the release of nitric oxide into the corpus cavernosum…