Antivirals
Antivirals PREGNANCY CATEGORY B OR C Therapeutic Actions Antiviral drugs inhibit viral DNA or RNA replication in the virus, preventing replication and leading to viral death. Indications Initial and recurrent…
Antimigraine Drugs (Triptans)
Antimigraine Drugs (Triptans) PREGNANCY CATEGORY C Therapeutic Actions Triptans bind to serotonin receptors to cause vascular constrictive effects on cranial blood vessels, causing the relief of migraine in selective patients….
Antimetabolites
Antimetabolites DANGEROUS DRUG PREGNANCY CATEGORY D Therapeutic Actions Antimetabolites are antineoplastic drugs that inhibit DNA polymerase. They are cell-cycle-phase–specific to S phase (stage of DNA synthesis), causing cell death for…
Antihistamines
Antihistamines PREGNANCY CATEGORY B OR C Therapeutic Actions Antihistamines competitively block the effects of histamine at peripheral H1 receptor sites, have anticholinergic (atropine-like) and antipruritic effects. Indications Relief of symptoms…
Antifungals
Antifungals PREGNANCY CATEGORY C Therapeutic Actions Antifungals bind to or impair sterols of fungal cell membranes, allowing increased permeability and leakage of cellular components and causing the death of the…
Antidiabetics
Antidiabetics PREGNANCY CATEGORY B, C (GLYBURIDE, METFORMIN) Therapeutic Actions Oral antidiabetics include several drug types. One type, called the sulfonylureas, stimulates insulin release from functioning beta cells in the pancreas…
Anticoagulants
Anticoagulants DANGEROUS DRUG PREGNANCY CATEGORY C (HEPARIN, APIXABAN, DABIGATRAN, RIVAROXABAN) PREGNANCY CATEGORY X (WARFARIN) PREGNANCY CATEGORY B (LOW–MOLECULAR-WEIGHT HEPARINS) Therapeutic Actions Oral anticoagulants interfere with the hepatic synthesis of vitamin…
Antiarrhythmics
Antiarrhythmics PREGNANCY CATEGORY C Therapeutic actions Antiarrhythmics act at specific sites to alter the action potential of cardiac cells and interfere with the electrical excitability of the heart. Most of…
Angiotensin II Receptor Blockers (ARBs)
Angiotensin II Receptor Blockers (ARBs) PREGNANCY CATEGORY D Therapeutic actions ARBs selectively block the binding of angiotensin II to specific tissue receptors found in the vascular smooth muscle and adrenal…
Angiotensin-Converting Enzyme (ACE) Inhibitors
Angiotensin-Converting Enzyme (ACE) Inhibitors PREGNANCY CATEGORY D Therapeutic actions ACE inhibitors block ACE in the lungs from converting angiotensin I, activated when renin is released from the kidneys, to angiotensin…
