Simvastatin

Simvastatin
(sim va stah’ tin)
Apo-Simvastatin (CAN), CO Simvastatin (CAN), Gen-Simvastatin (CAN), Novo-Simvastatin (CAN), PMS-Simvastatin (CAN), ratio-Simvastatin (CAN), Zocor
PREGNANCY CATEGORY X
Drug Classes
Antihyperlipidemic
HMG-CoA reductase inhibitor
Therapeutic Actions
Inhibits HMG-CoA reductase, the enzyme that catalyzes the first step in the cholesterol synthesis pathway, resulting in a decrease in serum cholesterol, serum LDLs, and either an increase or no change in serum HDLs.
Indications
  • Adjunct to diet in the treatment of hyperlipidemia
  • To reduce the risk of coronary disease, mortality, and CV events, including stroke, TIA, MI, and reduction in need for bypass surgery and angioplasty in patients with coronary heart disease and hypercholesterolemia
  • Treatment of adolescents 10–17 yr with heterozygous familial hypercholesterolemia
Available Forms
Tablets—5, 10, 20, 40, 80 mg
Dosages
Adults
Jul 21, 2016 | Posted by in NURSING | Comments Off on Simvastatin

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