Simvastatin



Simvastatin





(sim va stah’ tin)

Apo-Simvastatin (CAN), CO Simvastatin (CAN), Gen-Simvastatin (CAN), Novo-Simvastatin (CAN), PMS-Simvastatin (CAN), ratio-Simvastatin (CAN), Zocor

PREGNANCY CATEGORY X


Drug Classes

Antihyperlipidemic

HMG-CoA reductase inhibitor


Therapeutic Actions

Inhibits HMG-CoA reductase, the enzyme that catalyzes the first step in the cholesterol synthesis pathway, resulting in a decrease in serum cholesterol, serum LDLs, and either an increase or no change in serum HDLs.


Indications



  • Adjunct to diet in the treatment of hyperlipidemia


  • To reduce the risk of coronary disease, mortality, and CV events, including stroke, TIA, MI, and reduction in need for bypass surgery and angioplasty in patients with coronary heart disease and hypercholesterolemia


  • Treatment of adolescents 10–17 yr with heterozygous familial hypercholesterolemia



Available Forms

Tablets—5, 10, 20, 40, 80 mg


Dosages

Adults

Jul 21, 2016 | Posted by in NURSING | Comments Off on Simvastatin

Full access? Get Clinical Tree

Get Clinical Tree app for offline access