Palonosetron Hydrochloride



Palonosetron Hydrochloride





(pal on os’ e tron)

Aloxi

PREGNANCY CATEGORY B


Drug Classes

Antiemetic

Selective serotonin receptor antagonist


Therapeutic Actions

Selectively binds to serotonin receptors in the CTZ, blocking the nausea and vomiting caused by the release of serotonin by mucosal cells during chemotherapy, radiotherapy, or surgical invasion, an action that stimulates the CTZ and causes nausea and vomiting.


Indications



  • Prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of moderately and highly emetogenic chemotherapy


  • Prevention of postoperative nausea and vomiting for up to 24 hr after surgery (IV)



Available Forms

Injection—0.25 mg/5 mL


Dosages

Adults

Jul 21, 2016 | Posted by in NURSING | Comments Off on Palonosetron Hydrochloride

Full access? Get Clinical Tree

Get Clinical Tree app for offline access