Chapter 3. Nurses and the pharmaceutical service
The working relationship between pharmacist and nurse33
Drug selection and dosage34
Drug supply34
Drug storage34
Drug preparation35
Drug labels35
Drug administration35
Observing the effects of drugs36
Information needs of nurses37
Legal responsibility of nurses as regards drugs37
In the community37
Dosage calculations38
Summary of pharmaceutical services available to nurses38
At the end of this chapter, the reader should be able to:
• state the information needed by patients in relation to their medication and how to take it
• describe the regulations under the Misuse of Drugs Act and the Medicines Act which affect the nurse
• discuss the nurse’s responsibilities for the safe storage and handling of drugs
• describe the procedures for handling hazardous drugs such as cytotoxic drugs
• describe how to monitor the effects of drugs by measuring, for example, temperature, blood pressure, urine output and proteinuria, according to the drug administered and the condition being treated
The working relationship between pharmacist and nurse
In hospital the overall responsibility for the care and supply of drugs lies with the pharmacist, who will advise on their handling and use. The nurses’ responsibilities for the handling of drugs fall into seven areas: they will obtain drugs, possibly prescribe them, store them, prepare and administer them to patients, record the administration, and observe their effects, in accordance with the requirements of the law and with hospital protocols and procedures. In all of these activities they are able to call upon the pharmacist for help and advice.
A close working relationship can be built up between nurses and pharmacists where there is an active clinical pharmacy service attached to the ward. The usual practice is for the pharmacist to visit the ward once or twice a day, to see the prescription sheets, initiate the dispensing of any drugs required, raise any queries on dosage, availability or incompatibility with the doctor, and offer any drug information required by the doctor or nurse. By doing this, the pharmacist very quickly becomes familiar with the requirements of the ward, both in terms of supply and information, and can play a considerable part in ensuring the safe handling and use of drugs. Many pharmacists in hospital attend ward rounds as part of the clinical team to ensure that pharmaceutical care is provided appropriately to patients from admission to discharge.
Drug selection and dosage
In hospital, doctors and nurse prescribers need to be aware that their trust is very likely to have its own local drug formulary, which combines treatment guidelines and recommends ‘best-buy’ drugs from the often bewildering range available, and gives information on dosage, routes of administration, costs, contraindications and side-effects. Hospital pharmacies usually stock only those drugs listed in the formulary.
Drug supply
Drugs in frequent use in a ward, or likely to be required in an emergency, are usually supplied as ward stock. In most hospitals the pharmacy operates a top-up system with a pharmacy technician checking and supplying drugs to an agreed stock level on a weekly basis, thus removing the responsibility of ordering from the nurse. Whichever system is used, the aim must be to avoid both wasteful overstocking and running out at times when the pharmacy is closed.
Individual patient dispensing is used for less frequently required drugs and in cases where the preparation is tailored to the patient’s particular requirements. Although most drugs are manufactured by industry, hospital pharmacies are always able to prepare different dose forms or strengths; for example, a mixture for a patient unable to take solids, a paediatric mixture where the child needs a lower dose, or a suppository if the oral route is contraindicated. Some hospitals are able to prepare injections of novel or little-used chemicals, or formulate a chemical substance into preparations suitable for administration by a variety of routes. These more expert services, although concentrated in a few hospitals, are available to all through service contracts. The ward pharmacist can always advise on a suitable preparation and arrange for it to be made available.
The law requires that drugs of addiction, known as controlled drugs, must be supplied only against the signature of a qualified nurse or midwife, usually the nurse in charge of the ward or his or her deputy, and that the requisitions for these drugs must state precisely the name, form, strength and quantity of the drug required. Controlled drugs most likely to be met by the nurse include morphine, diamorphine (heroin), methadone, dextromoramide, buprenorphine and fentanyl. In addition, some hospitals place similar controls on other drugs liable to misuse, such as night sedatives, tranquillizers and antidepressants, and on spirits such as whisky and brandy.
Drug storage
All drugs are potentially dangerous and all must be stored in locked cupboards reserved specifically for drugs. Ward sisters and charge nurses are legally authorized to possess controlled drugs for use on their wards (but not for any other purpose) and these and all other drugs issued to the ward are in their custody. Keys to the drug cupboards must be held by a sister or charge nurse, or their deputies. Drugs in current use may be stored in drug trolleys, provided that these are locked and immobilized between drug rounds. Topical preparations such as ointments, lotions and disinfectants are also dangerous if misused, and these too must be locked in cupboards.
Storage conditions are important for most drugs and it is the pharmacist’s responsibility to ensure that the label on the container bears adequate instructions such as ‘store in a refrigerator’. Drugs which need cool or cold storage will begin to deteriorate if left at room temperature for more than a few hours, and if this happens the pharmacist’s advice must be sought – it is not sufficient to put the drug in the fridge after 2 days and hope for the best.