Micafungin Sodium(mick ah fun’ gin)
Mycamine
PREGNANCY CATEGORY C
Drug Classes
Antifungal
Echinocandin
Therapeutic Actions
Inhibits the synthesis of components needed for the production of fungal cell walls, leading to cell death.
Indications
Treatment of patients with esophageal candidiasis
Prevention of Candida infections in patients undergoing hematopoietic stem cell transplantation
Treatment of candidemia, acute disseminated candidiasis, Candida peritonitis and abscesses
Contraindications and Cautions
Contraindicated with known hypersensitivity to micafungin.
Use cautiously with liver impairment, renal impairment, pregnancy, lactation.
Available Forms
Powder for injection—50, 100 mg
Dosages
Adults
Treatment of esophageal candidiasis: 150 mg/day by IV infusion over 1 hr for 10–30 days.
Prophylaxis of Candida infection: 50 mg/day by IV infusion over 1 hr for about 19 days.
Treatment of Candida infections: 100 mg/day IV infused over 1 hr for 10–47 days based on infection being treated.
Pediatric patients 4 mo and older
Treatment of esophageal candidiasis: More than 30 kg, 2.5 mg/kg/day (maximum, 150 mg/day) IV over 1 hr for 10–30 days; 30 kg or less, 3 mg/kg/day IV over 1 hr for 10–30 days.
Prophylaxis of Candida infections: 1 mg/kg/day IV over 1 hr for about 19 days (maximum, 100 mg/day).
Treatment of Candida infections: 2 mg/kg/day IV over 1 hr for 10–47 days based on infection being treated.
