Hereditary Breast and Ovarian Cancer Syndrome


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CHAPTER 7


Hereditary Breast and Ovarian Cancer Syndrome


CHAPTER OBJECTIVES




  • Describe the genes involved in hereditary breast and ovarian cancer.
  • Identify risks associated with mutations in breast cancer genes.
  • Detail the impacts of the founder effect and penetrance.
  • Discuss management options for patients at risk for or affected by hereditary breast and/or ovarian cancer.

KEY TERMS



BRCA1


BRCA2


Cowden syndrome


Founder effect


Germline mutation


Kindred


Li-Fraumeni syndrome (LFS)


Peutz-Jeghers syndrome (PJS)


PTEN hamartoma tumor syndrome (PHTS)


Tumor suppressor gene


Tumorigenesis

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  1. Introduction
  2. Chronic Myelogenous Leukemia
  3. Hereditary Cardiomyopathies
  4. Ethical, Legal, and Social Issues

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Mar 23, 2020 | Posted by in NURSING | Comments Off on Hereditary Breast and Ovarian Cancer Syndrome

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