Hemolytic disease (erythroblastosis fetalis)

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  Hemolytic disease of the fetus and neonate
  
  
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  Stems from an incompatibility of fetal and maternal blood
  
  
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  Complications possible including fetal death in utero, severe anemia, heart failure, and kernicterus
  
  
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  Also known as hemolytic disease of the newborn

Causes

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  ABO incompatibility
  
  
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  Rh isoimmunization (see What happens in Rh isoimmunization, page 106)
  
  
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  Rh negativity—more common in Whites than Blacks and rare in Asians
  
  
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  Rh sensitization—11 cases per 10,000 births
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