FelodipineDNC(fell oh’ di peen)
PlendilDNC, Renedil (CAN)DNC
PREGNANCY CATEGORY C
Drug Classes
Antihypertensive
Calcium channel blocker
Therapeutic Actions
Inhibits the movement of calcium ions across the membranes of cardiac and vascular smooth muscle cells; greater selectivity for vascular smooth muscle as compared to cardiac muscle; leads to arterial and coronary artery vasodilation and decreased peripheral vascular resistance.
Indications
Essential hypertension, alone or in combination with other antihypertensives
Available Forms
ER tabletsDNC—2.5, 5, 10 mg
Dosages
Adults
Initially, 5 mg PO daily; dosage may be gradually increased over at least 14 days. Usual dose is 2.5–10 mg PO daily. Doses greater than 10 mg PO daily are associated with an increased risk of peripheral edema.
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