Clarithromycin(klar ith’ ro my sin)
Biaxin, Biaxin XLDNC
PREGNANCY CATEGORY C
Drug Classes
Macrolide antibiotic
Therapeutic Actions
Inhibits protein synthesis in susceptible bacteria, causing cell death.
Indications
Treatment of URIs caused by Streptococcus pyogenes, Streptococcus pneumoniae
Treatment of lower respiratory infections caused by Mycoplasma pneumoniae, S. pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Haemophilus parainfluenzae
Treatment of skin and skin structure infections caused by Staphylococcus aureus, S. pyogenes
Treatment and prevention of disseminated mycobacterial infections due to Mycobacterium avium and Mycobacterium intracellulare
Treatment of active duodenal ulcer associated with Helicobacter pylori in combination with proton pump inhibitor
Treatment of acute otitis media, acute maxillary sinusitis due to H. influenzae, M. catarrhalis, S. pneumoniae
Treatment of mild to moderate community-acquired pneumonia
Contraindications and Cautions
Contraindicated with hypersensitivity to clarithromycin, erythromycin, or any macrolide antibiotic.
Use cautiously with colitis, hepatic or renal impairment, pregnancy, lactation.
Available Forms
Tablets—250, 500 mg; granules for suspension—125, 250 mg/5 mL; ER tabletsDNC—500 mg
Dosages
Adults
Pharyngitis, tonsillitis; pneumonia due to: S. pneumoniae, M. pneumoniae; skin or skin structure infections; lower respiratory infections due to S. pneumoniae, M. catarrhalis: 250 mg PO every 12 hr for 7–14 days.
Stay updated, free articles. Join our Telegram channel
Full access? Get Clinical Tree
