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CHAPTER 9
Chronic Myelogenous Leukemia
CHAPTER OBJECTIVES
- Describe hematology associated with chronic myelogenous leukemia.
- Detail signs and symptoms associated with chronic myelogenous leukemia.
- Define the Philadelphia chromosome.
- Provide an overview of current treatments and factors associated with recovery from chronic myelogenous leukemia.
KEY TERMS
Chronic myelogenous leukemia (CML)
Fluorescence in situ hybridization (FISH)
Polymerase chain reaction (PCR)
Leukemia is the term used to describe a cancer in blood cells that are produced in the bone marrow. Specifically, leukemia of the granulocytic cell line in the bone marrow may be either acute or chronic. Chronic myelogenous leukemia (CML) is categorized as a myeloproliferative disorder (overproduction) that is usually insidious in onset, progressing slowly over many months to years.
KEY TERM
Chronic myelogenous leukemia (CML): a myeloproliferative disorder characterized by increased proliferation of the granulocytic cell line without the loss of their capacity to differentiate.
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