Treatment of pharyngitis, tonsillitis caused by Streptococcus pyogenes; otitis media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, S. pyogenes; respiratory infections caused by S. pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Escherichia coli, Klebsiella, H. influenzae, S. pyogenes; UTIs caused by E. coli, Klebsiella pneumoniae; dermatologic infections caused by S. aureus, S. pyogenes, E. coli, Klebsiella, Enterobacter; uncomplicated and disseminated gonorrhea caused by Neisseria gonorrhea; septicemia caused by S. pneumoniae, S. aureus, E. coli, Klebsiella, H. influenzae; meningitis caused by S. pneumoniae, H. influenzae, S. aureus, Neisseria meningitidis; bone and joint infections caused by S. aureus

Perioperative prophylaxis

CNS: Headache, dizziness, lethargy, paresthesias, seizures

GI: Nausea, vomiting, diarrhea, anorexia, abdominal pain, flatulence, pseudomembranous colitis, hepatotoxicity

GU: Nephrotoxicity

Hematologic: Bone marrow depression; decreased WBC, platelets, Hct

Hypersensitivity: Ranging from rash, fever to anaphylaxis; serum sickness reaction