Treatment of lower respiratory infections: Acute bacterial exacerbations of COPD due to Haemophilus influenzae, Moraxella catarrhalis, Streptococcus pneumoniae; community-acquired pneumonia due to S. pneumoniae, H. influenzae, Mycoplasma pneumoniae; Chlamydophila pneumoniae

Treatment of lower respiratory infections: Streptococcal pharyngitis and tonsillitis due to Streptococcus pyogenes in those who cannot take penicillins

Treatment of genital ulcer disease caused by Haemophilus ducreyi (chancroid) in men

Treatment of uncomplicated skin infections due to Staphylococcus aureus, S. pyogenes, Streptococcus agalactiae

Treatment of nongonococcal urethritis and cervicitis due to Chlamydia trachomatis; treatment of PID

Treatment of otitis media caused by H. influenzae, M. catarrhalis, S. pneumoniae in children older than 6 mo

Treatment of pharyngitis and tonsillitis caused by S. pyogenes in children older than 2 yr who cannot use first-line therapy

Prevention and treatment of disseminated Mycobacterium avium complex (MAC) in patients with advanced HIV infection

Treatment of patients with mild to moderate acute bacterial sinusitis caused by H. influenzae, M. catarrhalis, S. pneumoniae (Zmax)

Treatment of mild to moderate community-acquired pneumonia caused by C. pneumoniae, H. influenzae, M. pneumoniae, S. pneumoniae (Zmax)

Treatment of bacterial conjunctivitis (AzaSite)

Unlabeled uses: Uncomplicated gonococcal infections caused by N. gonorrhoeae, gonococcal pharyngitis caused by N. gonorrhoeae, chlamydial infections caused by C. trachomatis, prophylaxis after sexual attack, babesiosis, early Lyme disease, granuloma inguinale, treatment of cholera in adults, treatment of cystic fibrosis (as an anti-inflammatory)