Zanamivir(zan am’ ah ver)
Relenza Diskhaler
PREGNANCY CATEGORY C
Drug Classes
Antiviral
Neuroaminidase inhibitor
Therapeutic Actions
Selectively inhibits influenza virus neuroaminidase; by blocking the actions of this enzyme, there is decreased viral release from infected cells, increased formation of viral aggregates, and decreased spread of the virus.
Indications
Prevention and treatment of uncomplicated acute illness due to influenza virus in adults and children 7 yr and older who have been symptomatic for no more than 2 days
Prevention of influenza in patients 5 yr and older
Unlabeled use: Treatment of H1N1 infection
Contraindications and Cautions
Contraindicated with allergy to any component of the drug.
Use cautiously with pregnancy, lactation, asthma, COPD, severe medical conditions, neuropsychiatric problems.
Available Forms
Powder blister for inhalation—5 mg
Dosages
Adults and children 7 yr and older
Treatment: Two inhalations (one 5-mg blister per inhalation administered with a Diskhaler device, for a total of 10 mg) bid at 12-hr intervals for 5 days. Should be started within 2 days of onset of flu symptoms; give two doses on the first treatment day, at least 2 hr apart; subsequent doses should be separated by 12 hr.
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