Zaleplon(zal’ ah plon)
Sonata
PREGNANCY CATEGORY C
CONTROLLED SUBSTANCE C-IV
Drug Class
Sedative-hypnotic (nonbenzodiazepine)
Therapeutic Actions
Interacts with GABA-B2 receptor complex to cause suppression of neurons leading to sedation and hypnosis.
Indications
Short-term treatment of insomnia
Contraindications and Cautions
Contraindicated with hypersensitivity to zaleplon, tartrazine; lactation.
Use cautiously with impaired hepatic or respiratory function, depression, history of drug abuse/dependence, pregnancy, labor and delivery.
Available Forms
Capsules—5, 10 mg
Dosages
Adults
10 mg PO at bedtime. Patient must remain in bed for 4 hr after taking the drug. Do not exceed 20 mg/day.
Pediatric patients
Safety and efficacy not established.
Geriatric patients or debilitated patients
5 mg PO at bedtime. Do not exceed 10 mg/day.
Patients with hepatic impairment
Mild to moderate impairment: 5 mg/day
Severe impairment: Not recommended.
