Somatropin



Somatropin





(soe ma troe’ pin)

Genotropin, Genotropin Miniquick, Humatrope, HumatroPen, Norditropin, Nutropin, Nutropin AQ, Nutropin AQ Pen, Omnitrope, Saizen, Serostim, Tev-Tropin, Zorbtive

PREGNANCY CATEGORY C

PREGNANCY CATEGORY B (GENOTROPIN, OMNITROPE, SAIZEN, SEROSTIM, ZORBTIVE)


Drug Class

Hormone


Therapeutic Actions

Hormone of recombinant DNA origin; contains the identical amino acid sequence of pituitary-derived human growth hormone; therapeutically equivalent to endogenous growth hormone; stimulates skeletal (linear) growth, growth of internal organs, protein synthesis, many other metabolic processes required for normal growth.


Indications



  • All but Serostim: Long-term treatment of children with growth failure due to lack of adequate endogenous growth hormone secretion


  • Nutropin and Nutropin AQ: Treatment of children with growth failure related to chronic renal failure, chronic renal insufficiency, up to the time of renal transplantation


  • Genotropin, Norditropin, Nutropin, Nutropin AQ, and Humatrope, HumatroPen: Treatment of girls suffering from Turner syndrome


  • Serostim: Treatment of AIDS wasting and cachexia to increase lean body mass and improve physical endurance


  • Genotropin: Long-term treatment of children with growth failure due to Prader-Willi syndrome (PWS)


  • Genotropin: Long-term treatment of growth failure in children of small gestational age (SGA) who do not catch up by 2 yr


  • Genotropin, Norditropin, Nutropin, Nutropin AQ, Humatrope, Omnitrope, Saizen: Growth hormone deficiency (GHD) in adults


  • Humatrope, HumatroPen: Treatment of short stature or growth failure in children with short staturehomeobox (SHOX)-containing gene deficiency whose epiphyses have not closed.



  • Humatrope, Norditropin: Treatment of short stature in children of SGA who do not present with catch-up growth by 2–4 yr


  • Humatrope, Nutropin, Nutropin AQ, Humatropen, Genotropin: Long-term treatment of idiopathic short stature in pediatric patients whose epiphyses are not closed and for whom diagnostic evaluation excludes other causes treatable by other means


  • Norditropin Treatment of short stature in children with Noonan syndrome or Turner syndrome


  • Norditropin: Treatment of adults with severe GHD


  • Saizen, Genotropin, Humatrope, Humatropen, Norditropin, Nutropin, Nutropin AQ, Omnitrope: Replacement of endogenous growth hormone in adults with GHD who have GHD alone or in combination with multiple hormone deficiencies as a result of pituitary disease, hypothalamic disease, surgery, radiation therapy, or trauma or who had GHD as a child and who have had continued GHD established as an adult


  • Zorbtive: Treatment of short bowel syndrome in patients receiving specialized nutritional support

Jul 21, 2016 | Posted by in NURSING | Comments Off on Somatropin

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