Impetigo presents as a red rash with many small blisters that may be itchy and break easily. Once the blisters rupture they are covered by honey-colored crusts.

Bullous impetigo (impetigo neonatorum) is a superficial skin infection of neonates that usually affects the buttocks, perineum, trunk, face, and extremities. The blisters form in response to toxins produced by the bacteria, are filled with fluid, and rupture easily within 24 to 48 hours. Little crust formation occurs after rupture. Oral and topical antibiotics are used to treat the infection. Because bullous impetigo is highly contagious, the infant should be isolated in the nursery to prevent spread to other infants.

Impetigo contagiosa is a common, highly contagious, superficial skin infection caused by the staphylococci (Staphylococcus aureus) and/or streptococci (Streptococcus pyogenes) bacteria. The face, arms, and legs are the most often affected. It is most common in the summer, and children with poor hygiene or those in daycare settings are especially susceptible to developing impetigo. The infected child’s washcloths, towels, drinking glass, clothing, and bed linen should not be shared to prevent infecting others.