Rosuvastatin Calcium



Rosuvastatin Calcium





(row sue’ va sta tin)

Crestor

PREGNANCY CATEGORY X


Drug Classes

Antihyperlipidemic drug

HMG-CoA reductase inhibitor (statin)



Therapeutic Actions

A fungal metabolite that inhibits the enzyme (HMG-CoA) that catalyzes the first step in the cholesterol synthesis pathway, resulting in a decrease in serum cholesterol, serum LDLs (associated with increased risk of coronary artery disease) and either an increase or no change in serum HDLs (associated with decreased risk of coronary artery disease).


Indications



  • As an adjunct to diet in the treatment of elevated total cholesterol and LDL cholesterol and triglyceride levels in patients with primary hypercholesterolemia (familial and nonfamilial), and in patients with mixed dyslipidemia


  • Adjunct to diet to slow atherosclerosis progression in patients with elevated cholesterol


  • As an adjunct to diet for the treatment of patients with elevated serum triglyceride levels


  • To reduce LDL-C, total cholesterol, and ApoB in patients with homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering treatments or if such treatments are not available


  • Treatment of patients with primary dysbetalipoproteinemia


  • Treatment of children 10–17 yr (girls must be at least 1 yr postmenarchal) with heterozygous familial hypercholesterolemia when diet therapy fails


  • Primary prevention of CV disease; to reduce risk of stroke, MI, and arterial revascularization procedures in patients with no clinically evident CAD but at increased risk due to age (50 and older in men, 60 and older in women), elevated C-reactive protein, and at least one other risk factor (hypertension, low HDL, smoking, family history)



Available Forms

Tablets—5, 10, 20, 40 mg


Dosages

Adults

Jul 21, 2016 | Posted by in NURSING | Comments Off on Rosuvastatin Calcium

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