Ranolazine



Ranolazine





(ran oh’ lah zeen)

RanexaDNC

PREGNANCY CATEGORY C


Drug Classes

Antianginal

Piperazineacetamide


Therapeutic Actions

Antianginal, anti-ischemic. Mechanism of action is not known. Prolongs the QT interval; does not decrease HR or BP; decreases myocardial workload.


Indications



  • Treatment of chronic angina



Available Forms

ER tabletsDNC—500, 1,000 mg


Dosages

Adults

500 mg PO bid; may be increased to maximum of 1,000 mg bid.

Pediatric patients

Safety and efficacy not established.

Patients with hepatic impairment

Not recommended with mild, moderate, or severe hepatic impairment.


Pharmacokinetics















Route Onset Peak
Oral Rapid 2–5 hr

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Jul 21, 2016 | Posted by in NURSING | Comments Off on Ranolazine

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