Raloxifene Hydrochloride(rah lox’ i feen)
Evista
PREGNANCY CATEGORY X
Drug Class
Selective estrogen receptor modulator
Therapeutic Actions
Increases bone mineral density without stimulating endometrium in women; modulates effects of endogenous estrogen at specific receptor sites.
Indications
Prevention and treatment of osteoporosis in postmenopausal women
Reduction of risk of invasive breast cancer in postmenopausal women with osteoporosis and a high risk of invasive breast cancer
Unlabeled uses: Uterine leiomyoma, pubertal gynecomastia, prevention of bone loss in men with prostate cancer
Contraindications and Cautions
Contraindicated with allergy to raloxifene, pregnancy, lactation, premenopause, active or history of DVT, PE, or retinal vein thrombosis.
Use cautiously with history of smoking, venous thrombosis.
Pharmacokinetics
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