Questions and Answers
PART III · QUESTIONS
1. Which of the following statements concerning vitamin B12 is correct?
a. Vitamin B12 is absorbed in the stomach.
b. Vitamin B12 requires extrinsic factor for absorption.
c. Vitamin B12 excess is stored in parietal cells for later use.
d. Vitamin B12 contains cobalt.
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1. The correct answer is d. Vitamin B12 is absorbed in the ileum and requires intrinsic factor manufactured by parietal cells in the stomach for absorption. Excess amounts are stored in the liver.
2. The nurse reviewing lab results recognizes that the reticulocyte count represents the
a. Rate at which RBCs are being recycled and broken down
b. Amount of iron stored in the liver
c. Rate of RBC production
d. Amount of transferrin available to transport iron
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2. The correct answer is c. New, not fully matured RBCs are called reticulocytes. They are produced in the bone marrow and sent into circulation. Their amount indicates how fast or slow the bone marrow is making new RBCs and is a first indicator that therapy for iron deficiency anemia is working.
3. Which anemia is associated with depression, polypharmacy, and poor appetite?
a. Iron deficiency
b. Anemia of chronic disease
c. Thalassemia
d. Folic acid deficiency
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3. The correct answer is b. People with chronic illnesses, in addition to the underlying chronic condition itself, often suffer from the problems listed, making it difficult for them to take in and use sufficient iron to meet body requirements.
4. When parents, each having the sickle cell trait, have a child, and one parent passes on the sickle cell gene, the child will
a. have sickle cell disease
b. carry the sickle cell trait
c. not have a sickle cell defect
d. die in utero
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4. The correct answer is b. This is a heterozygous situation; with only one gene passed on, the child has the trait and will be essentially asymptomatic.
5. What treatment is required for pernicious anemia that results from a gastrectomy?
a. Iron by mouth daily for 6 months
b. Oral cobalamin daily
c. Folate supplements daily for life
d. Vitamin B12 injections monthly for life
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5. The correct answer is d. Pernicious anemia is an autoimmune disease in which the individual can no longer absorb vitamin B12 from the gut and needs to have it supplemented monthly for life.
6. What does an individual with thalassemia minor experience?
a. Premature death
b. Mental retardation
c. Mild chronic hemolytic anemia
d. Growth failure and bony deformities
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6. The correct answer is c. Those with thalassemia minor experience a persistent mild anemia that they compensate for with increased RBC production. The other choices are all sequelae of thalassemia major, which is a severe, life-threatening disorder.