Pyrantel Pamoate(pi ran’ tel)
Combantrin (CAN), Panix, Pin-Rid, Pin-X, Reese’s Pinworm
PREGNANCY CATEGORY C
Drug Class
Anthelmintic
Therapeutic Actions
A depolarizing neuromuscular blocking agent that causes spastic paralysis of Enterobius vermicularis and Ascaris lumbricoides. Also effective against Ancyclostoma duodenale (hookworm).
Indications
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Treatment of enterobiasis (pinworm infection)
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Treatment of ascariasis (roundworm infection), trichinosis
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Unlabeled use: Hairworm
Contraindications and Cautions
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Contraindicated with allergy to pyrantel pamoate.
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Use cautiously with pregnancy, lactation, hepatic disease.
Available Forms
Oral suspension—50 mg/mL, 144 mg/mL; chewable tablets—720.5 mg
Dosages
Adults and pediatric patients older than 2 yr
11 mg/kg (5 mg/lb) PO as a single oral dose. Maximum total dose of 1 g.
Pediatric patients younger than 2 yr
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