Pentoxifylline(pen tox ih’ fileen)
Pentoxifylline SR (CAN), TrentalDNC
PREGNANCY CATEGORY C
Drug Classes
Hemorrheologic drug
Xanthine
Therapeutic Actions
Reduces RBC aggregation and local hyperviscosity, decreases platelet aggregation, decreases fibrinogen concentration in the blood; precise mechanism of action is not known.
Indications
Intermittent claudication, to improve function and symptoms
Contraindications and Cautions
Contraindicated with allergy to pentoxifylline or methylxanthines (eg, caffeine, theophylline; drug is a dimethylxanthine derivative); recent cerebral or retinal hemorrhage.
Use cautiously with renal impairment, pregnancy, lactation.
Available Forms
ER tabletsDNC—400 mg
