
See Appendix R, Less commonly used drugs.
Omega-3-Acid Ethyl Esters
(oh may gah-three-ass’ id)
Lovaza
PREGNANCY CATEGORY C
Drug Classes
Lipid-lowering drug
Omega-3 fatty acid
Therapeutic Actions
Inhibits liver enzyme systems leading to a decrease in the synthesis of triglycerides in the liver, lowering serum triglyceride levels.
Indications
As an adjunct to diet to reduce very high (greater than 500 mg/dL) triglyceride levels in adult patients
Contraindications and Cautions
Contraindicated with known allergy to any component of the capsule.
Use caution with known sensitivity to fish products, pregnancy, lactation.
Available Forms
Capsules—1 g
Dosages
Adults
4 g/day PO taken as a single dose (4 capsules) or divided into two doses—2 capsules PO bid.
Pediatric patients
Safety and efficacy not established.
Pharmacokinetics
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