Norfloxacin



Norfloxacin





(nor flox’ a sin)

Apo-Norflox (CAN), CO-Norfloxacin (CAN), Noroxin

PREGNANCY CATEGORY C


Drug Classes

Antibiotic

Fluoroquinolone

Urinary tract anti-infective


Therapeutic Actions

Bactericidal; interferes with DNA replication in susceptible gram-negative bacteria, leading to cell death.


Indications



  • For the treatment of adults with UTIs caused by susceptible bacteria, including Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Enterobacter cloacae, Proteus vulgaris, Providencia rettgeri, Morganella morganii, Proteus aeruginosa, Citrobacter freundii, Staphylococcus aureus, S. epidermidis, group D streptococci


  • Uncomplicated urethral and cervical gonorrhea caused by Neisseria gonorrhoeae


  • Prostatitis caused by E. coli


  • Unlabeled uses: GI infections, traveler’s diarrhea



Available Forms

Tablets—400 mg


Dosages

Adults



  • Uncomplicated UTIs: 400 mg every 12 hr PO for 7–10 days. Maximum dose, 800 mg/day.


  • Uncomplicated cystitis due to E. coli, K. pneumonia, or P. mirabilis: 400 mg every 12 hr PO for 3 days.



  • Complicated UTI: 400 mg PO every 12 hr for 10–21 days.


  • Uncomplicated gonorrhea: 800 mg PO as a single dose.


  • Prostatitis: 400 mg every 12 hr PO for 28 days.

Pediatric patients

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Jul 21, 2016 | Posted by in NURSING | Comments Off on Norfloxacin

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