Non-Hodgkin’s lymphoma

Description
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Includes lymphosarcoma, reticulum cell sarcoma, and Burkitt’s lymphoma
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Prognosis for aggressively treated localized disease: nearly 90% survival; for advanced disease, survival greater than 60%
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Also known as malignant lymphoma
Pathophysiology
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Although similar to Hodgkin’s disease, Reed-Sternberg cells aren’t present, and lymph node destruction is different.
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Lymphoid tissue is defined by the pattern of infiltration as diffuse or nodular; nodular lymphomas yield a better prognosis than the diffuse form, but prognosis (for both forms) is less hopeful than in Hodgkin’s disease.
Causes
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Unknown, although some theories suggesting a viral source for some cases
Assessment findings
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Varied symptoms depending on the organ involved
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Enlarged lymph nodes, most commonly in the lower cervical region, including tonsils and adenoids
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