Nafarelin Acetate



Nafarelin Acetate





(naf’ a re lin)

Synarel

PREGNANCY CATEGORY X


Drug class

Gonadotropin-releasing hormone (GnRH)


Therapeutic Actions

A potent agonistic analogue of GnRH, which is released from the hypothalamus to stimulate LH and FSH release from the pituitary; these hormones are responsible for regulating reproductive status. Repeated dosing abolishes the stimulatory effect on the pituitary gland, leading to decreased secretion of gonadal steroids by about 4 wk; consequently, tissues and functions that depend on gonadal steroids for their maintenance become quiescent.


Indications



  • Treatment of endometriosis, including pain relief and reduction of endometriotic lesions


  • Treatment of central precocious puberty in children of both genders



Available Forms

Nasal solution—2 mg/mL (200 mcg/spray)


Dosages

Adults

Jul 21, 2016 | Posted by in NURSING | Comments Off on Nafarelin Acetate

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