Nabumetone



Nabumetone





(nah byoo’ meh tone)

Apo-Nabumetone (CAN), Gen-Nabumetone (CAN)

PREGNANCY CATEGORY C

(FIRST AND SECOND TRIMESTERS)

PREGNANCY CATEGORY D

(THIRD TRIMESTER)


Drug Classes

Analgesic (nonopioid)

NSAID


Therapeutic Actions

Analgesic, anti-inflammatory, and antipyretic activities largely related to inhibition of prostaglandin synthesis; exact mechanisms of action are not known.


Indications



  • Acute and long-term treatment of signs and symptoms of rheumatoid arthritis and osteoarthritis



Available Forms

Tablets—500, 750 mg


Dosages

Adults

1,000 mg PO as a single dose with or without food. 1,500–2,000 mg/day have been used. May be given in divided doses.

Pediatric patients

Safety and efficacy not established.

Patients with renal impairment

Maximum starting dose should not exceed 750 mg daily for moderate insufficiency, 500 mg for severe insufficiency.

Jul 21, 2016 | Posted by in NURSING | Comments Off on Nabumetone

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