Mumps
Description
Acute inflammation of one or both parotid glands or the sublingual or submaxillary glands
Also called infectious or parotitis
Pathophysiology
Paramyxovirus is found in the saliva of an infected person.
It’s transmitted by droplets or by direct contact with the saliva of an infected person.
Causes
Necrosis of acinar and epithelial duct cells in the salivary glands and germinal epithelium of the seminiferous tubules
Perivascular and interstitial mononuclear cell infiltrating with edema, due to infection of the central nervous system (CNS) or glandular tissues (or both)
Virus replication in the epithelium of the upper respiratory tract, leading to viremia
Focus inParotid inflammation in mumps
The mumps virus (paramyxovirus) attacks the parotid glands — the main salivary glands. Inflammation causes characteristic swelling and discomfort associated with eating, swallowing, and talking.
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