Major Depressive Disorder
Depression is an affective state characterized by feelings of sadness, guilt, and low self-esteem. It may be a chronic condition or an acute episode, often related to loss. This loss may or may not be recent and may be observable to others or perceived only by the client, such as disillusionment or loss of a dream. Depression may be seen in grief, the process of a normal response to a loss; premenstrual syndrome (PMS), a complex of symptoms that begins the week prior to menstrual flow; and postpartum depression, which occurs after childbirth and may involve symptoms from mild depressive feelings to acute psychotic behavior.
A
major depressive episode is characterized by a depressed mood or loss of interest or pleasure in almost all activities for at least 2 weeks, in addition to at least four other depressive symptoms. These include appetite, weight, or sleep changes; a decrease in energy or activity; feelings of guilt or worthlessness; decreased concentration; or suicidal thoughts or activities. A
major depressive disorder is diagnosed when one or more of these episodes occur without a history of manic (or hypomanic) episodes. When there is a history of manic episodes, the diagnosis is
bipolar disorder (see
Care Plan 27: Bipolar Disorder, Manic Episode). The duration and severity of symptoms and degree of functional impairment of depressive behavior vary widely, and the diagnosis of major depressive disorder is further described as
mild, moderate, severe without psychotic features, or
severe with psychotic features (
APA, 2000).
Major depressive disorder occurs more frequently in people with chronic or severe medical illnesses (e.g., diabetes, stroke) and in people with a family history of depression. Theories of the etiology of depression focus on genetic, neurochemical, hormonal, and biologic factors, as well as psychodynamic, cognitive, and social/behavioral influences.
Prevalence of major depressive disorder in adults is estimated to be between 2% and 3% in men and between 5% and 9% in women. The lifetime risk of major depressive disorder is estimated at 8% to 12% in men and 20% to 26% in women (
Gorman, 2006). Depressive behavior frequently occurs in clients during withdrawal from alcohol or other substances, and in clients with anorexia nervosa, phobias, schizophrenia, a history of abuse, post-traumatic behavior, poor social support, and so forth.
The average age of a person with an initial major depressive episode is in the midtwenties, although it can occur at any age. Approximately 66% of clients experience a full recovery from a depressive episode, but most have recurrent episodes over time. Symptoms of depressive episodes last a year or more in many clients (
APA, 2000).
Treatment usually involves antidepressant medications (see
Appendix E: Psychopharmacology). It is important for the nurse to be knowledgeable about medication actions, timing of effectiveness (certain drugs may require up to several weeks to achieve the full therapeutic effect), and side effects. Teaching the client and family or significant others about safe and consistent use of medications is essential. Other therapeutic goals include maintaining the client’s safety; decreasing psychotic symptoms; assisting the client in meeting physiologic needs and hygiene; promoting self-esteem, expression of feelings, socialization, and leisure skills; and identifying sources of support.
NURSING DIAGNOSES ADDRESSED IN THIS CARE PLAN
Ineffective Coping
Impaired Social Interaction
Bathing Self-Care Deficit
Dressing Self-Care Deficit
Feeding Self-Care Deficit
Toileting Self-Care Deficit
Chronic Low Self-Esteem
RELATED NURSING DIAGNOSES ADDRESSED IN THE MANUAL
Social Isolation
Disturbed Thought Processes
Risk for Other-Directed Violence
Risk for Suicide
Complicated Grieving
Insomnia
Hopelessness