Table 19-1 Stages of Menopause | ||||||||||||||||||||||||||||||
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Menopause
Menopause
QUICK LOOK AT THE CHAPTER AHEAD
Menopause is defined as the cessation of menses for 12 consecutive months. The age at which menopause occurs is predetermined genetically. There are several possible stages of menopause: perimenopause, menopause, induced menopause, premature menopause, and postmenopause. Currently, diagnosing menopause is based solely on the patient’s symptomatology. Traditionally, measuring a serum estradiol, follicle-stimulating hormone (FSH), and luteinizing hormone (LH) were enough to determine whether a woman was in menopause.
Consequences of menopause include increased risk of cardiovascular disease, hypertension, hyperlipidemia, and osteoporosis or osteopenia.
Treatment options for menopause include hormone therapy (HT), which continues to be controversial, and complementary or alternative therapies. Life-style changes are also recommended to help reduce menopausal symptoms.
Menopause is defined as the cessation of menses for 12 consecutive months. It is also referred to as the climacteric phase of a woman’s life. The average age of menopause in the United States is 51 years of age. Women today can expect more than one-third of their lives to be ahead of them when they reach menopause and have a mean life expectancy of 84 years. The age at which menopause occurs is predetermined genetically as is the onset of menarche in young women. A woman can expect menopause at about the same age that her mother or older sisters experienced it. Cigarette smoking can increase the onset of menopause by about 2 years. Table 19-1 describes the different stages of menopause.
Menopause is defined as the cessation of menses for 12 consecutive months. It is also referred to as the climacteric phase of a woman’s life. The average age of menopause in the United States is 51 years of age. Women today can expect more than one-third of their lives to be ahead of them when they reach menopause and have a mean life expectancy of 84 years.
PATHOPHYSIOLOGY
Ovaries are responsible for the production of estrogen and progesterone as well as small amounts of androgens, including testosterone, which are responsible for a woman’s libido. The other function of the ovaries is to produce eggs. At birth, the ovaries contain approximately a half million follicles, which decrease with age. When puberty occurs, the follicles mature to become eggs. As the number of follicles or eggs decrease, estrogen levels begin to decrease. Approximately 90% of all circulating estrogen is produced by the ovaries; however, androgens produced by the adrenal glands convert the adipose cells into estrogen.
The pituitary gland produces follicle-stimulating hormone (FSH) and luteinizing hormone (LH). FSH causes stimulation of the follicles to develop, whereas LH causes the release of the egg from the ovary. The biofeedback between the ovaries, the hypothalamus, and the pituitary gland must be well regulated for menstruation to occur. As the ovary produces less estrogen and progesterone, FSH and LH levels rise and irregular menses occur. Ultimately, the production of ovarian follicles ceases, leading to decreased estrogen and progesterone levels while FSH and LH levels remain high. This causes menstruation to stop.