Lorcaserin Hydrochloride



Lorcaserin Hydrochloride





(lore cass’ ah rin)

Belviq

PREGNANCY CATEGORY X


Drug Classes

Serotonin receptor agonist

Weight loss drug


Therapeutic Actions

Thought to decrease food consumption and promote satiety by selectively activating the serotonin-2C receptors in the anorexigenic neurons in the hypothalamus.


Indications



  • Adjunct to diet and exercise for long-term weight management in adults with initial body mass index (BMI) of 30 kg/m2 or greater or 27 kg/m2 or greater with at least one weight-related condition, such as hypertension or dyslipidemia



Available Forms

Tablets—10 mg


Dosages

Adults

10 mg PO bid without regard to food; if patient has not lost 5% of baseline weight within 12 wk, drug should be discontinued.


Pharmacokinetics















Route Onset Peak
Oral Rapid 1.5–2 hr

Metabolism: Hepatic: T1/2: 11 hr

Distribution: May cross placenta; may enter breast milk

Excretion: Urine

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Jul 21, 2016 | Posted by in NURSING | Comments Off on Lorcaserin Hydrochloride

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