Hyperemesis gravidarum
Severe and unremitting nausea and vomiting that persists after the first trimester
Usually occurs with the first pregnancy and commonly affects pregnant women with conditions that produce high levels of human chorionic gonadotropin, such as gestational trophoblastic disease or multiple gestations
Causes
Exact cause unknown; linked to trophoblastic activity, gonadotropin production, and psychological factors
Various possible causes
Pancreatitis (elevated serum amylase levels are common)
Biliary tract disease
Decreased secretion of free hydrochloric acid in the stomach
Decreased gastric motility
Drug toxicity
Inflammatory obstructive bowel disease
Vitamin deficiency (especially of B6)
Psychological factors (in some cases)
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